Uroš Kuzmanović, Phd Email & Phone Number

Boston, Ma, Us

Cambridge, Massachusetts, Us

Engineering novel wearables to enable health ownership.2024-MIT E-Lab Host Company [Fall]-MDIC AMCH Grant Awardee-MIT.nano START.nano Cohort Member-ARPA-H Investor Catalyst Member-MLSC Women's Health Collaboration Program Host Company-MassVentures START Stage I Awardee-MIT E-Lab Host Company [Spring]-NSF SBIR Phase II Grant Awardee2023-FORGE Fall Startup Showcase Finalist-Fifty Years 5050 Cohort 3 Member-RBPC Finalist-NVIDIA Inception Program Member-2048 Ventures Biotech Pitch Competition Semi-Finalist-TiE ScaleUp Accelerator Cohort Finalist2022 -Hello Tomorrow Deep Tech Pioneer-TiE Boston Rising Entrepreneur of the Year Award -IMPACT Accelerator Cohort Finalist-Pepperdine Most Fundable Companies Semi-Finalist-BSU Hustle Project Nominee-Hatch@Nest.Bio Award Winner-TiE University Global Pitch Competition 1st Place Winner-M2D2 $200K Challenge 1st Place Winner-MIT Sloan Healthcare Innovations Prize Finalist-TiE University Regional Pitch Competition 1st Place Winner-Nucleate Accelerator Cohort Finalist2021-Biogen Lab Central Golden Ticket Finalist-NSF Beat-the-Odds Bootcamp Team Lead-MIT E-Lab Host Company [Fall]-M2D2 Barracuda Bowl Presenter-Novo Nordisk Lab Central Golden Ticket Semi-Finalist-Boston University Bench to Bedside Host Company Lead-NSF STTR Phase I Grant Awardee-MassChallenge Accelerator Cohort Finalist-BU Ignition Award Winner-M2D2 $200K Challenge 2nd Place Winner

Cambridge, Massachusetts, Us

2020-NSF NE I-Corps Spark Program Team Lead

Boston, Ma, Us

Precision Diagnostic Center (PDC)Prof. James Galagan- Novel Biosensors (DARPA, USU, ONR)Genomically mined nature to identify cellular machinery for the production of physiological biosensors for civilian and military use. Under this project I am developing novel nicotine, hormone, and neurotransmitter biosensors which can monitor noninvasively through human sweat, urine, and saliva. - Antibiotic Resistance (Philips)To combat microbial antibiotic resistance, I have screened for gene signatures in response to antibiotics and stresses in drug sensitive and resistant bacterial strains.

Boston, Ma, Us

Biomedical Measurements Lab (BE 491)- Taught students how to: 1) collect and analyze biomedical signals 2) operate electronic equipment such as the oscilloscope, function generator, and DAQ 3) effectively communicate their scientific findings orally and through written reports 4) Experimentally validate theoretical concepts such as Fourier Analysis, sampling, and filtering.

Boston, Ma, Us

Us

Carl R. Woese Institute for Genomic Biology (IGB)Energy BioScience Institute (EBI)Prof. Yong-Su Jin & Dr. Soo Rin Kim- Metabolic Engineering (EBI)Elucidated the underlying mechanism for efficient cellulosic bioethanol production in S. cerevisiae expressing a heterologous xylose pathway. This was done by perturbing the genome of S. cerevisiae strains in order to understand the mechanism and role of a HAD phosphatase, Pho13 enzyme, through assessment of gene expression levels by various RNA quantification techniques, incubations, and assays. Assessment included investigating global transcriptional changes as a result of Pho13 deletion and the observation of the resulting oxidative stress response and phenotype.

Champaign, Il, Us

Roger Adams Laboratory (RAL)Prof. Paul J. Hergenrother- Drug Discovery Focused on the development of novel small molecules to inhibit complexation between MBNL1 splicing regulator proteins and CUG RNA repeats to treat myotonic dystrophy type I (DM1). In order to do so I designed a low-cost and time efficient electrophoretic mobility shift assay which was able to preliminarily screen small molecules that disrupt complexation between disease specific RNA and MBNL. Using the developed assay, the toxicity of previously selected and designed compounds was determined by culturing HeLa cell plates as well as disease specific DM1 patient cell lines in order to test compound viability in vivo. Assessed effectiveness of selected compounds by visualizing disruption of the RNA-MBNL complexation through disruption of fluorescent foci in cell culture by confocal microscopy.

Cambridge, Massachusetts, Us

University of Illinois at Urbana-Champaign iGEM 2012Carl R. Woese Institute for Genomic Biology (IGB)Energy BioScience Institute (EBI)Prof. Yong-Su Jin & Prof. Christopher V. Rao- Idea to RealizationModeled and synthesized a one-dimensional RNA scaffold designed to create an in vivo enzymatic assembly line for efficient and cost-effective commercial production of chemical compounds. The scaffold was made using an online software (Freiburg RNA Tools) and through communication with a doctoral student under Prof. Pamela Silver (Harvard University). Proved scaffold function through EMSA using site specific RNA binding proteins tethered to non-specific endonucleases through collaboration with Prof. Zefeng Wang (UNC-Chapel Hill) and further characterized the RNA scaffold through AFM imaging.

Belgrade, Rs

Medical SchoolInstitute of Human DiseasesProf. Tatjana M. DamnjanovicStudied single nucleotide polymorphisms in first trimester miscarriage patients.

Doctor Of Philosophy (Phd), Biomedical Engineering

Master Of Science (Ms), Biomedical Engineering

Leap Program, Engineering

Bachelor Of Science (Bs), Molecular And Cellular Biology, Chemistry Minor