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Umut Cagin Email & Phone Number
Principal Scientist
at
AAVantgarde Bio
LinkedIn matched
3 data sources
Profile completeness 86%
Current company
Role
Principal Scientist
Location
Philadelphia, Pennsylvania, United States
Company size
Who is Umut Cagin? Overview
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Quick answer
Umut Cagin is listed as Principal Scientist at AAVantgarde Bio, a company with 55 employees, based in Philadelphia, Pennsylvania, United States. AeroLeads shows a matched LinkedIn profile for Umut Cagin.
Umut Cagin previously worked as Senior Research Scientist at Spark Therapeutics, Inc. and Postdoctoral Researcher at Genethon. Umut Cagin holds Doctor Of Philosophy - Phd, Molecular Neuroscience from King'S College London.
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AAVantgarde Bio
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Profile bio
About Umut Cagin
Self-motivated scientist with strong background in gene therapy, metabolism, rare diseases, muscular diseases and molecular neuroscience. Over a decade of experience performing translational research with proven track record in leading successful research projects, mentoring, and publications. Experience in running cross-functional programs concurrently from target identification to efficacy and safety studies in academic institutes and biotech settings. Experience in drafting non-clinical sections of regulatory documents and interactions with regulatory agencies.
Current workplace
Umut Cagin's current company
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Aavantgarde Bio
5 roles
Umut Cagin work experience
A career timeline built from the work history available for this profile.
Senior Research Scientist
Current- Gene Therapy R&D; Systemic Gene Therapy Group
- Lead in vitro and in vivo studies spanning early discovery through IND-enabling stages of AAV gene therapy development (PoTP, PoC, dose-finding and GLP toxicology) for rare metabolic and liver diseases
- Develop program strategies through comprehensive disease and target landscape analysis for nonclinical data packages to support regulatory filings; execute strategic plan through collaboration with cross-functional.
- Oversee translational biomarker studies using human patient material to inform design of pre-clinical and clinical studies; coordinate assay development with internal and external partners, presented data package at.
- Selected as Operations Committee Chair for the international community employee resource group (ERG); collaborate with leadership team to implement DE&I strategies and increase awareness across organization
Apr 2021 - Present
Postdoctoral Researcher
- Liver directed gene therapies lab (PI: Dr. Federico Mingozzi)
- Designed and executed in vitro and in vivo (rodent) PoTP and PoC studies for AAV-based gene therapies in models of rare metabolic diseases; resulted in 2 first author and 3 co-author primary research and review articles
- Optimized and implemented molecular biology assays (qPCR, western blotting, IHC, ELISA) and high throughput assays (RNASeq) to investigate disease mechanisms and effects of therapeutic candidates
- Mentored 2 BSc and 2 MSc students over the course of 4 years
- Secured competitive funding (Marie Skłodowska Curie - Individual Fellowship, EU)
Apr 2017 - Jan 2021
Postdoctoral Researcher
Cnic - Spanish National Center For Cardiovascular Research / Centro Nac. Investigaciones Cardiovasc.
- Genetics of Oxidative Phosphorylation lab (PI: Prof. Jose Antonio Enriquez)
- Generated and analyzed in vitro models of mitochondrial diseases to uncover novel molecular mechanisms of metabolic diseases
- Performed in-vitro gene editing using CRISPR/Cas9
- Performed standard molecular biology assays (qPCR, western blot, native PAGE, IHC), metabolic assays (respirometry, Seahorse XF),
- Performed transcriptomics using RNASeq, followed by big data analysis (in collaboration with bioinformatics unit)
- Mentored 1 BSc and 3 MSc students over the course of 4 years
Sep 2013 - Apr 2017
Postdoctoral Researcher
- Short term postdoctoral project (PI: Prof. Marzia Malcangio).
- Investigated molecular mechanisms of pain using established in vitro models
- Performed standard molecular biology assays (qPCR, western blotting, protein isolation and purification)
Jun 2013 - Sep 2013
2 education records
Umut Cagin education
Doctor Of Philosophy - Phd, Molecular Neuroscience
Bachelor Of Science - Bs, Molecular Biology And Genetics
FAQ
Frequently asked questions about Umut Cagin
Quick answers generated from the profile data available on this page.
What company does Umut Cagin work for?
Umut Cagin works for AAVantgarde Bio.
What is Umut Cagin's role at AAVantgarde Bio?
Umut Cagin is listed as Principal Scientist at AAVantgarde Bio.
Where is Umut Cagin based?
Umut Cagin is based in Philadelphia, Pennsylvania, United States while working with AAVantgarde Bio.
What companies has Umut Cagin worked for?
Umut Cagin has worked for Aavantgarde Bio, Spark Therapeutics, Inc., Genethon, Cnic - Spanish National Center For Cardiovascular Research / Centro Nac. Investigaciones Cardiovasc., and King'S College London.
How can I contact Umut Cagin?
You can use AeroLeads to view verified contact signals for Umut Cagin at AAVantgarde Bio, including work email, phone, and LinkedIn data when available.
What schools did Umut Cagin attend?
Umut Cagin holds Doctor Of Philosophy - Phd, Molecular Neuroscience from King'S College London.
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