Urs Weber Email & Phone Number

Amsterdam, 1105Bp, Nl

Mechelen, Belgium, Be

Reporting to the CMO, member of his/her leadership team: Accountable to lead the R&D Project Management Organization to deliver fit-for-purpose and state-of-the-art project and portfolio management expertise and leadership and provide central systems, reporting and analytics capabilities that enable integrated business planning and reporting; responsible to provide operational leadership to the CMO, his/her leadership team, and the broader Research and Development organizations; responsible for the Operating Model including governance and associated key governance committees- Established a fit-for-purpose R&D Project Management Organization (R&D PMO) by integrating decentralized project and portfolio management, end-to-end project planning and reporting, and operational expertise and capabilities to drive 30+ R&D projects- Led the R&D PMO of up to 60 people; supervised, developed, coached, and mentored staff members; helped individuals to grow their carrer and project teams to successfully navigate executive decision making- Oversaw end-to-end project and portfolio planning (schedule, cost, resources), execution, and delivery of all drug development projects with a yearly budget >€300M and 250-350FTEs- Managed the portfolio of 20+ development projects, led and facilitated executive project/portfolio reviews and decision-making- Led or contributed to several capability-building and two major organizational transformation projects incl. down-sizing R&D headcount by 20-30%

Mechelen, Belgium, Be

Tokyo, Jp, Jp

Strategic partner to the Global Internal Medicine Franchise Head and member of his/her cross-functional leadership team; responsible for outcome driven Franchise leadership team meetings; accountable for GPM-owned business processes and deliverables at Franchise level e.g. Franchise strategy, goals and objectives, R&D budget planning, risk management, decision making (governance), internal and external progress reporting, etc.Strategic partner to the Gastroenterology and Endocrinology Therapeutic Area Head and member of his/her leadership team; responsible for outcome driven leadership team and all-hands meetings; accountable for driving strategic and operational alignment of the Therapeutic Area with the FranchiseMember of the GPM leadership team; responsible for developing and implementing the functional (GPM) strategy; accountable for building, developing and leading a high-performing team of global program directors, deployed to Franchise aligned cross-functional product teams; accountable for overseeing program progress from research to commercialization and life-cycle management, and applying agreed good program management practices and standards across product teams, Therapeutic Areas and Franchises- Built the Global Program Management (GPM) team aligned to Shire's Internal Medicine Franchise; supervised, coached, and mentored a team of up to ten program directors- Developed and embedded the functional GPM strategy, value proposition, and standards including performance metrics- Oversaw the planning, execution, and delivery of all Franchise-aligned development projects- Provided program management expertise and leadership to the Franchise Head and his/her cross-functional leadership team; assumed Franchise chief-of-staff responsibilities- Co-led and contributed to the integration of the Shire R&D into the Takeda organization and operating model; facilitated work-shops to develop the Product Strategy Leader role description and value proposition

Tokyo, Jp, Jp

Strategic partner to the 2 product team leads (co-leadership model) and member of their cross-functional product team; responsible for outcome driven team meetings; responsible for delivering assigned programs to agreed plans, time-lines, cost and quality standards; responsible for cross-functional team effectiveness; accountable for program management owned business processes and deliverables at product level e.g. product strategy, integrated, cross-functional product plan, goals and objectives, risk management, decision making (governance), internal and external progress reporting, etc.- Project managed the post-acquisition integration of Natpar/Natpara® and associated regulatory submission to the EMA, approval, and launch in the EU (2016 CEO Award)- Led the Xagrid® pediatric development team; achieved a 2-year orphan drug exclusivity extension (2014 CEO Award)- Led and project managed Shire's first ever regulatory submission to the Japanese PMDA and the set-up of local commercialization capabilities

Tokyo, Jp, Jp

Strategic partner to the product team lead and member of his/her cross-functional product team; responsible for outcome driven team meetings; responsible for delivering as-signed programs to agreed plans, timelines, cost and quality standards; responsible for cross-functional team effectiveness; accountable for program management owned business processes and deliverables at product level e.g. product strategy, integrated, cross-functional product plan, goals and objectives, risk management, decision making (governance), internal and external progress re-porting, etc.

Tokyo, Jp, Jp

Partner to the product team lead and member of his/her cross-functional product team; responsible for outcome driven team meetings; accountable for program management owned business processes and deliverables at product level

Lausanne, Vaud, Ch

Direct reporting line to CEO; accountable for the development and execution of product manufacturing strategies and supply plans to enable phase 1 (liposomal vaccine and monoclonal antibody) and phase 2 (small molecule) clinical trials; accountable for the management of contract manufacturing organizations and analytical labs; responsible for the development and implementation of a project management and progress reporting framework including performance metrics; responsible for leading a cross-functional team and manage the Company’s early stage (pre-clinical to phase 2) drug development programs as per aforementioned framework- Project managed the development and submission of 2 clinical trial applications with accountability for CTD Modules 3- Timely delivered supplies for a Phase 1 (liposomal vaccine) and a Phase 2 (small molecule) clinical trials- Developed and implemented a fit-for-purpose project management and progress reporting framework including performance metrics

Darmstadt, De

Technical Operations functional representative on Global Product Teams in charge of the development and commercialization of recombinant proteins and monoclonal antibodies within the (Merck) Serono project-based organization; responsible for leading global project teams and driving the development and optimization of mammalian cell-lines, cell culture media, drug substance and drug product manufacturing processes including formulation, (bio)analytical methods for in-process controls and product release, and the design and execution of drug product stability and comparability studies, scale-up and tech-transfer from lab to pilot and/or large-scale production; accountable for project planning and execution including budgeting, goals and objective setting, risk management and progress/performance reporting to Global Product Teams and relevant supervisory committees and governance bodies- Led the development of the company’s first fed-batch manufacturing process including the scale-up and tech transfer from 3.5L to 300L and 2,500L scale- Led the post-acquisition integration of the company’s first mono-clonal antibody development program (CHO cell-line)

Darmstadt, De

Manager of a manufacturing process development lab and associated technical and scientific staff; responsible for leading and developing technical expert and project teams of up to 12 members (technicians, engineers and scientists i.e. PhDs); responsible for maintaining and further developing a state-of-the-art process development lab with 20+ 5L, 15L and 40L bioreactors, allocating equipment and executing production campaigns as per projects’ needs; responsible for leading assigned scale-up and tech transfer projects for the production and supply of phase 3 clinical trial material- Led the development and implementation of an integrated, cross-functionally aligned manufacturing process development blue-print (lean six sigma green belt certification project)

Darmstadt, De

Develop, scale-up and tech-transfer mammalian cell-culture fed-batch processes for the production of recombinant bulk products to supply late stage clinical trials; lead, motivate and coach a team of 6 to 8 associates