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- Drug discovery leader with significant managerial and project team leader experience.- Broadly trained life-sciences researcher with cross-disciplinary training and skills.- Deep expertise in GPCR biochemistry, molecular pharmacology, and drug discovery- Over 2 decades of experience with small molecule drug discovery R&D.
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Senior Vice President, Biological SciencesSepterna Mar 2021 - PresentSouth San Francisco, California, UsOur mission is to discover, develop, and commercialize medicines that improve the lives of patients by combining the potential of high-value GPCR drug targets with the power of state-of-the-art small molecule drug discovery technologies. Septerna’s Native Complex™ Platform is the engine that will make this happen, moving ideas for disease-modifying therapies from possibility to reality. -
Head Of In-Vitro BiologyBristol Myers Squibb Nov 2020 - Mar 2021Lawrence Township, Nj, UsLeading a team of biologists in the discovery of novel therapies for the treatment of cardiomyopathies and other forms of heart disease. Transitioning from MyoKardia following its acquisition by Bristol Myers Squibb in November 2020. -
Vice President, BiologyMyokardia Oct 2019 - Nov 2020Brisbane, California, UsTo change the world for people with serious cardiovascular diseases through bold and innovative science, MyoKardia is pioneering a precision medicine approach to treating cardiomyopathies and other forms of heart failure that results from biomechanical defects in cardiac muscle contraction. -
Vice President, BiologyNumerate, Inc. Oct 2014 - Sep 2019Drug Discovery R&D.Responsible for all aspects of Numerate’s experimental biology strategy. PI on two NIH SBIR grant funded projects (cardiac arrhythmias and bone disorders).Numerate seeks to overcome major challenges in drug discovery by applying artificial intelligence (AI), at cloud scale, to the problems of small-molecule drug design. Numerate was acquired by Valo Health (https://www.valohealth.com).
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Senior Director, Molecular & Cellular BiologyTheravance Biopharma, Inc. Sep 1998 - Oct 2014South San Francisco, Ca, UsDrug Discovery R&DDepartment: Molecular & Cellular BiologyExpertise: Small Molecule Drug Discovery, Molecular Pharmacology, Cell Biology, Biochemistry, Discovery Collaborations w. Partner Companies, Outsourced ResearchRole: Group Leader; Project Team LeaderTherapeutic Expertise: Cardiovascular, Respiratory -
Expert AdvisorEuropean Commission 2012 - 2013Brussels, BeMember of expert panel evaluating grant proposals for European Union FP7 Program -
Masters And Phd StudentMax Planck Institute Of Biophysics Jan 1989 - Feb 1995Frankfurt, DeMS student in Chemistry (1989-1990), worked on the synthesis and characterization of analogs of vasopressin and oxytocin; modification of the parent peptides with biotin and photoreactive groups to obtain tools for the biochemical characterization of the respective receptors. Continued work as a PhD student in Biochemistry (1990-1994) to use those tools for protein-chemical characterization of the guinea pig oxytocin receptor.
Uwe Klein Skills
Uwe Klein Education Details
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Stanford UniversityMolecular & Cellular Biology -
University Of California, San FranciscoMolecular & Cellular Biology -
University Of California, Santa CruzBioinformatics -
Goethe University FrankfurtBiochemistry -
Goethe University FrankfurtChemistry -
Goethe University FrankfurtChemistry
Frequently Asked Questions about Uwe Klein
What company does Uwe Klein work for?
Uwe Klein works for Septerna
What is Uwe Klein's role at the current company?
Uwe Klein's current role is Senior Vice President, Biological Sciences.
What is Uwe Klein's email address?
Uwe Klein's email address is uk****@****nce.com
What is Uwe Klein's direct phone number?
Uwe Klein's direct phone number is +165057*****
What schools did Uwe Klein attend?
Uwe Klein attended Stanford University, University Of California, San Francisco, University Of California, Santa Cruz, Goethe University Frankfurt, Goethe University Frankfurt, Goethe University Frankfurt.
What are some of Uwe Klein's interests?
Uwe Klein has interest in Christianity, Cooking, Exercise, Electronics, Traveling, Outdoors, International Traavel, Reading, Music, Family Values.
What skills is Uwe Klein known for?
Uwe Klein has skills like Drug Discovery, Biochemistry, Pharmaceutical Industry, Cell Biology, Assay Development, Biotechnology, Cell, Molecular Biology, Life Sciences, R&d, Lifesciences, Drug Development.
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