Frank Van Lier

Frank Van Lier Email and Phone Number

VP Technical Operations | CMC expert @ HyperMabs Inc.
Frank Van Lier's Location
Canada, Canada
Frank Van Lier's Contact Details

Frank Van Lier work email

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About Frank Van Lier

I like biopharmaceutical manufacturing and the science and engineering that is needed to develop products, processes, and organizations to turn a promising drug candidate into a drug product with a safety, an efficacy, and a production cost that allows it to reach the intended patients.I learned the importance of proper development to turn a candidate into a product and create Chemistry, Manufacturing and Control (CMC) programs appropriate for the different phases of clinical studies or for commercialization.I had the opportunity to work on wide variety of products in different phases of (clinical) development: recombinant proteins, viral vectors, vaccines, and cell therapies, using animal cells and/or microbes to produce these. To allow these products to be used in humans they must be produced in a Good Manufacturing Practices (GMP) compliant environment, and I did technology transfers from Research and Development to Manufacturing working for an R&D team or working for a manufacturing team.I was involved as expert in GMP facility and equipment design, participated or led their commissioning, validation, and start-up and implemented quality systems.I learned a lot from the people I work(ed) with, and I led, hired, managed, trained and/or mentored co-workers. I like sharing my experience and knowledge through training and lectures.

Frank Van Lier's Current Company Details
HyperMabs Inc.

Hypermabs Inc.

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VP Technical Operations | CMC expert
Frank Van Lier Work Experience Details
  • Hypermabs Inc.
    Vice President, Technical Operations
    Hypermabs Inc. Jul 2023 - Present
    HyperMabs is a biopharmaceutical company that designs and developsinnovative monoclonal antibody-based therapeutics for life threateningdiseases.
  • Excellthera
    Vice President Manufacturing
    Excellthera Nov 2021 - May 2023
    Montreal, Quebec, Canada
    ExCellThera is a clinical stage cell and molecular medicine company delivering molecules andbioengineering solutions to expand stem and immune cells for use in novel curative therapies forpatients with hematologic malignancies.▪︎ Preparing a CMC package for commercial submission of a cell-therapy product.▪︎ Supporting clinical production.
  • National Research Council Canada / Conseil National De Recherches Canada
    R&D Director Bioprocess Engineering Department, Human Health Therapeutics
    National Research Council Canada / Conseil National De Recherches Canada Dec 2015 - Nov 2021
    Montreal, Canada Area
    NRC's Human Health Therapeutics research centre works hand in hand with industry to help biotech firms achieve success and save costs. As an R&D partner of choice, NRC‑HHT de‑risks critical steps in the development of biologics, vaccines and immunotherapeutics, and delivery of large molecules to the brain, to help improve the health of Canadians. Responsible for the Bioprocess Engineering department (up to 135 researchers):▪︎ Expression and production of large molecules such as antibodies and viral vectors.▪︎ Process development and scale-up of the associated microbial and animal-cell based processes.▪︎ Purification of the products to a level where the process is suitable for transfer to a cGMP manufacturing organization.
  • National Research Council Canada
    Section Head Process Development And Scale-Up
    National Research Council Canada Apr 2015 - Nov 2021
    Montreal, Canada Area
    The Process Development and Scale Up team is engaged in a number of ongoing research services and collaborations with numerous biopharmaceutical companies to advance the development of their biologics and vaccines. Customized solutions are developed in partnership with our clients and collaborators, who work side-by-side with our scientists to ensure efficient technology transfer.
  • Frank Van Lier Consultancy
    Consultant Biotechnology/Pharmaceutical Processing
    Frank Van Lier Consultancy 2009 - Apr 2015
    Montreal, Canada Area
    Main mandates:Involved with design, construction and start-up of the Centre d'excellence en thérapie cellulaire (CETC) of the Hôpital Maisonneuve-Rosemont.Quality Assurance manager for a veterinary vaccine company.Quality consultant for the National Research Council.
  • Kiadis Pharma
    Senior Director R&D / Site Manager Montreal
    Kiadis Pharma 2008 - 2009
    Saint-Laurent, Canada
    Kiadis focuses on the R&D of cell therapeutics.▪︎ Process development.▪︎ Support clinical trials.▪︎ Managing of the Montreal site.
  • Laporte Consultants
    Bioprocess Specialist
    Laporte Consultants 2006 - 2008
    Montreal, Canada
    Laporte provides high value-added engineering services to pharmaceutical, agrifood and bioindustrial plants.▪︎ Conceptual and detailed design of process equipment and facilities.▪︎ Main projects: pharmaceutical pilot plant and microbial vaccine production facility.
  • Université De Montréal
    Director Operations Laboratoire De Biotechnologie Vétérinaire Et Alimentaire
    Université De Montréal 2005 - 2006
    Saint-Hyacinthe, Canada
    The Laboratoire de biotechnologie vétérinaire et alimentaire was intended as a GMP compliant production unit.▪︎ Setting up operations for production and development.▪︎ Validation of building and building systems.▪︎ Validation of process equipment for production in microbial and animal-cell platforms.
  • Dsm Biologics
    Senior Scientist And Manager Positions Within Operations Department
    Dsm Biologics 1997 - 2005
    Montreal, Canada
    DSM Biologics was a contract manufacturing organization for biological products.▪︎ Production of recombinant proteins up to 2000 scale.▪︎ Process transfer and process development.▪︎ Fed-batch and perfusion production.
  • Gist-Brocades / Bio-Intermediair
    Fermentation Supervisor
    Gist-Brocades / Bio-Intermediair 1994 - 1996
    Groningen, Netherlands
    Bio-Intermediair was a start-up company and a contract manufacturer for the biopharmaceutical industry located in The Netherlands and in Canada.▪︎ Start up GMP production.▪︎ Process transfer and production rec. proteins and vaccine.▪︎ Microbial and animal-cell platforms.▪︎ Batch, fed-batch and perfusion production.
  • Biocat Foundation
    Bioprocess Engineer
    Biocat Foundation 1992 - 1993
    Groningen, Netherlands
    The BioCat foundation had as mandate to develop biotechnology in the province of Groningen in The Netherlands.▪︎ Implementation of GMP Quality System at a CMO.▪︎ Validation of equipment and building systems.

Frank Van Lier Skills

Pharmaceutical Industry R&d Biopharmaceuticals Fermentation Documentations Training Biotechnology Sop Start Ups Product Development Fda Gmp Quality System Validation Chemical Engineering Chromatography Regulatory Affairs Analytical Chemistry Technology Transfer Clinical Development Hplc Lifesciences Cell Biology Quality Assurance Capa Microbiology Biochemistry V&v Process Simulation Project Management Drug Development Manufacturing Protein Chemistry Cell Culture Chemistry Molecular Biology Glp Change Control Process Engineering Life Sciences Research And Development

Frank Van Lier Education Details

Frequently Asked Questions about Frank Van Lier

What company does Frank Van Lier work for?

Frank Van Lier works for Hypermabs Inc.

What is Frank Van Lier's role at the current company?

Frank Van Lier's current role is VP Technical Operations | CMC expert.

What is Frank Van Lier's email address?

Frank Van Lier's email address is va****@****ail.com

What is Frank Van Lier's direct phone number?

Frank Van Lier's direct phone number is (613)-990*****

What schools did Frank Van Lier attend?

Frank Van Lier attended Wageningen University & Research.

What skills is Frank Van Lier known for?

Frank Van Lier has skills like Pharmaceutical Industry, R&d, Biopharmaceuticals, Fermentation, Documentations, Training, Biotechnology, Sop, Start Ups, Product Development, Fda, Gmp.

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