Vasudharani Devanathan Email & Phone Number

Tirupati Area, India

Lectures, tutorials and practical sessions to BS-MS students. Chair of students activities: to this position, I manage the student related issues in the campus together with 4 other colleagues. In IISER Tirupati, we call it COSA. Committee on Student's activities. Hostel issues, student's interpersonal issues, cultural activities, sports activities, student magazine, cultural activity, educational activities such as DAAD workshops, USIEF presentations, working together with the student… Show more Lectures, tutorials and practical sessions to BS-MS students. Chair of students activities: to this position, I manage the student related issues in the campus together with 4 other colleagues. In IISER Tirupati, we call it COSA. Committee on Student's activities. Hostel issues, student's interpersonal issues, cultural activities, sports activities, student magazine, cultural activity, educational activities such as DAAD workshops, USIEF presentations, working together with the student counsellors towards student's related psychological issues. Its a very interesting position! Show less

Chennai Area, India

Two weeks teaching on cell biology module to doctoral students (computational biology).Taught them cellular metabolism, cell motility and cytoskeleton, intracellular transport, cell cycle, channels and receptors, cell signalling-signal transduction and cell death.

Vadodara Area, India

Teaching specific topic modules in Cell biology, Biochemistry and Tissue culture to students admitted to Integrated M.Sc in cell and molecular biology. Organizing summer training in the campus and placing students for summer training programs in various research institutes.

Germany

Since two years I have been contributing to the journal club section of lab times and the editorial online.Here I communicate to authors of published research papers and write a journal club article.In the editorial section online, I write commentary about published research articles.

Tübingen Area, Germany

Project 1: Cell signalling in G protein knock out mice with special focus on cardiovascular system. Here I use knock out mice models to decipher G protein signalling mechanisms and specifically to show the role of G proteins-Galphai2 and Galphai3 in cardiovascular stroke Project 2: To understand the role of Galphai2 and Galphai3 in platelet signalling and thrombosis.My techniques include cell culture, in vitro techniques and in vivo techniques to understand the above… Show more Project 1: Cell signalling in G protein knock out mice with special focus on cardiovascular system. Here I use knock out mice models to decipher G protein signalling mechanisms and specifically to show the role of G proteins-Galphai2 and Galphai3 in cardiovascular stroke Project 2: To understand the role of Galphai2 and Galphai3 in platelet signalling and thrombosis.My techniques include cell culture, in vitro techniques and in vivo techniques to understand the above mentioned aim. Protein interaction studies, transmigration assays on isolated platelets and neutrophils, Cell protrusion assays, Cell adhesion assays, Elisa, surface biotinylation assays, are few methods that I regularly employ.Apart from bench my key role was also to write papers, grants and permits for animal experiment.Established active collaborations with several labs in Germany: 1) Rudolf Virchow centre, University of Wuerzburg. 2) Charite institute in Berlin, 3) Department of Anesthesiology, University of Tuebingen. Show less

Cell signalling in G protein knock out mice with special focus on cardiovascular system. I use knock out mice models to decipher G protein signalling mechanisms and specifically to show the role of G proteins-Galphai2 and Galphai3 in cardiovascular stroke and platelet signalling. I established Ischemia reperfusion surgical studies in G protein knock out mice. Ischemia was induced by occluding left anterior descending artery transiently and reperfusion was achieved by subsequent restoration… Show more Cell signalling in G protein knock out mice with special focus on cardiovascular system. I use knock out mice models to decipher G protein signalling mechanisms and specifically to show the role of G proteins-Galphai2 and Galphai3 in cardiovascular stroke and platelet signalling. I established Ischemia reperfusion surgical studies in G protein knock out mice. Ischemia was induced by occluding left anterior descending artery transiently and reperfusion was achieved by subsequent restoration of blood flow. This model was used to study the above mentioned aim. Show less

I was involved in designing, implementation and analysis of four independent projects. Here I have used and developed multiple methodologies involving cell-based and molecular biology based assays and in vivo animal experiments.

Here my project was understand the role of Prion proteins in brain. My PhD research led to the finding that Prion protein interacts with Contactin associated protein in the brain. In my PhD work, I standardised and established assays such as neurite outgrowth assay from primary cerebellar neurons, transfection studies in immortalised cell lines such as CHO cells and N2A cells, transfection studies in primary cerebellar neurons, surface biotinylation studies in immortalised cells, immuno… Show more Here my project was understand the role of Prion proteins in brain. My PhD research led to the finding that Prion protein interacts with Contactin associated protein in the brain. In my PhD work, I standardised and established assays such as neurite outgrowth assay from primary cerebellar neurons, transfection studies in immortalised cell lines such as CHO cells and N2A cells, transfection studies in primary cerebellar neurons, surface biotinylation studies in immortalised cells, immuno precipitation assays and Elisa assays. Show less

Hamburg

Designing, planning and performing cell biology and biochemistry experiments. Maintaining animal colonies and cell culture.

Performing MIC assays for in-house developed anti-mycobacterial compounds in Mycobacterium smegmatis and Mycobacterium tuberculosis (BSL-2 and BSL-3 facility). Development of luciferase based reporter assay.

Astra Zeneca India is actively involved in novel drug discovery for infectious diseases such as tuberculosis. Here I was involved in screening for in house synthesised compounds by minimum inhibitory concentration and minimum bactericidal concentration (MIC and MBC assays) using Mycobacterial strains-Mycobacterium smegmatis in the biosafety level 2 (BSL 2) and Mycobacterium tuberculosis H37Rv in biosafety level 3 (BSL 3).Thus actively involved in identification of lead compounds for… Show more Astra Zeneca India is actively involved in novel drug discovery for infectious diseases such as tuberculosis. Here I was involved in screening for in house synthesised compounds by minimum inhibitory concentration and minimum bactericidal concentration (MIC and MBC assays) using Mycobacterial strains-Mycobacterium smegmatis in the biosafety level 2 (BSL 2) and Mycobacterium tuberculosis H37Rv in biosafety level 3 (BSL 3).Thus actively involved in identification of lead compounds for tuberculosis. Show less

Chennai Area, India

I was working on a project-titled Isolation and characterization of Mycobacteriophages from soil samples. Our aim was to find a lysogenic phage that can be used in a phage based reporter assay.

Phd, Biology

I used biochemical methods and cell biological techniques such as DNA and protein transfections, primary cell culture, siRNA-based assays.

M.Sc, Microbiology

Activities and Societies: Participated in diabetes run conducted by Novo nordisk for diabetes awareness. Participated in a paper.

B.Sc, Microbiology, University 15Th Rank