Vathan Kumar Email & Phone Number

Cambridge, Massachusetts, United States

Multistep synthesis of new nucleosides with modified sugars, and ionizable lipids for LNP's.

Taiwan

Designing new delivery material for nanotherapeutics and understand SPR.Using rational approach to design polar and non-polar moiety to circumvent patent.

Taiwan

Establishment/setup new organic chemistry laboratory from bottom level.Designed new analog of Sotrastaurin, a selective pan-PKC inhibitor, using bioisoteric and scaffold hopping approach to replace its maleimide core. Drug repurposing, making new drug conjugates to modulate gut microbiota.Working with various collaborators and deliver required small.

Taipei City, Taiwan

• Accomplished rational design and synthesis of potent small molecule to disrupt protein-protein interactions between CCT-β:β-tubulin complex to selectively kill cancers and designed fluorescent probes to identify.
• Successfully used structure-based approach to design new inhibitor of bacterial UPPS which can be developed further.
• Synthesizing of probes to assess mechanism of cis-and trans-prenyltransferases.
• Designed targeted covalent inhibitors as anticancer and antibacterial agents.
• Developed small molecule to selectively disrupt protein-protein interactions between XIAP:caspase-7 to kill cancers overexpressing caspase-7.
• Discovered potent peptidomimetic inhibitor of MERS-CoV 3CLpro.

Bangalore

• Teaching experience with 300+ students of D.Pharm and B.Pharm in subjects like Biochemistry, Medicinal Chemistry and Pharmacology.
• Experience imparting practical training in medicinal and organic chemistry laboratories to 300+ students.
• Arranging examination schedule for internal exams.
• Served as external evaluator for practical examinations and invigilator for D.Pharm and B.Pharm exams at various examination centers.
• On-time completion of assignment as one of the custodian at Rajiv Gandhi University of Health Sciences by coordinating with experienced evaluators; assess deviations as per university standards between evaluators and.

Phd, Chemical Biology And Drug Design

Activities and Societies: Badminton, Cricket .. Successfully improvised neuraminidase inhibitor to 30 times more potent compound to kill.

Doctor Of Philosophy (Ph.D.), Chemical Biology And Molecular Biophysics

Activities and Societies: • Student representative for TIGP-CBMB program at Graduate Students Association. 2009-2011 Admitted to Taiwan.

Master'S Degree, Medicinal And Pharmaceutical Chemistry, Distinction

Activities and Societies: Part of the college Volleyball team. • Designed and synthesized new pyrimidine derivatives as bacterial.

Bachelor'S Degree, Pharmacy, Pharmaceutical Sciences, And Administration, First Class

Activities and Societies: Organizing sports events as sport secretary (2nd B.Pharm) Overseeing and managing all events General secretary.

Chemistry 130A: Pharmaceutical Chemistry

Activities and Societies: Quarterly Abroad Program at Academia Sinica , Taiwan Provide an introduction to the chemical principles behind.

Chem 130B: Computer Modeling For Drug Design

Activities and Societies: Quarterly Abroad Program at Academia Sinica, Taiwan This course provided hands-on experience with modern.