Vinoth Babu Veedin Rajan, Phd Email & Phone Number

Vienna, Austria

Research Areas: Adult Neurogenesis, Adult Neural Stem Cell, Circadian clock mutations, Genome editing, CRISPR, Clock mouse model✔︎ Directed a proactive research team and spearheaded 3 interdisciplinary projects, supported by FWF-SFB grant, to explore the intricate interplay between the biological clock and adult neurogenesis in both invivo and invitro conditions, employing advanced techniques from neurology, stem cell research, molecular biology, genetics, and imaging. ✔︎ Explored Adult Neural Stem Cell Dynamics: Conducted in-depth research on various cell types within adult neural stem cells, investigating the role of the circadian clock in their transitions from quiescence to activation and differentiation. ✔︎ Drove the entire research process, from experimental design and detailed data analysis. Ensured accurate interpretation of results and effective dissemination to advisory boards, demonstrating a commitment to meticulous research methodology. ✔︎ Pioneered novel humanized circadian clock knock-ins using CRISPR-CAS9 technology mimicking human depressive disorders and reporter lines in mice, highlighting innovative contributions to the field. ✔︎ Expertly managed laboratory operations, displaying strong managerial acumen by mentoring Ph.D. scholar and directly supervising research technicians. Fostered a collaborative and productive research environment, emphasizing teamwork and skill development. ✔︎ Showcased research findings at international conferences and symposiums, actively contributing to scientific discourse, and Initiated 3 strategic scientific collaborations.

Vienna, Austria

Research Areas: Circadian and Behavioural Neuroscience, Seasonal Affective Disorder (SAD), Natural light data, Data mining, RNAseq, Proteomics✔︎ Coordinated and led a diverse team of scientists, funded by the European Research Council steering innovative interdisciplinary projects spanning molecular biology, neurobiology, proteomics, and field experiments.✔︎ Successfully headed 4 pivotal projects focused on photoreceptors in biological clock function, involving experimental design, comprehensive data analysis, and effective communication of findings at conferences and to funding agencies. ✔︎ Drove groundbreaking discoveries, identifying deep-brain PRC ciliary opsin1 as a seasonal sensor and visual rhabdomeric opsin1 as a dual photo- and mechanosensor, showcasing expertise in neurobiology and photoreceptor functionality. ✔︎ Implemented advanced protocols for untargeted proteomics, and targeted neuro-peptidomics using LC- MS/MS, highlighting technical prowess in utilizing cutting-edge scientific methodologies to derive meaningful insights. ✔︎ Published 4 significant research articles in prestigious international peer-reviewed scientific journals, underscoring significant contributions to the field of biological clock research and demonstrating a commitment to advancing scientific knowledge.

Vienna, Austria

Research Areas: Biological clock, Deep Brain Photoreceptors, Device development, Real-time HR automated video recording systems, Quantitative analysis, Software development, Data mining✔︎ Led 4 pivotal research projects delving into the intricate roles of photoreceptors in circadian, mechanosensory, and circalunar clock functions. ✔︎ Conceived, structured, and managed comprehensive project scopes, meticulously defining experimental goals and timelines. Successfully handled resources and mitigated risks while diligently monitoring project progress.✔︎ Pioneered the establishment of advanced behavioral analysis systems, including high-resolution automated recording setups and a sophisticated quantifiable locomotor analysis software prototype, essential for comprehending Platynereis behavior.✔︎ Co-developed the experimental chamber mimicking Natural Environmental Light Intensity Systems (NELIS) to study/compare the Platynereis clock function at natural and laboratory conditions. ✔︎ Contributed significantly to the inception of LoopBio, a Vienna-based startup, by providing a proof of concept for cutting-edge behavioral analysis technology, thereby fostering entrepreneurial innovation in the scientific community. ✔︎ Developed a robust data analysis framework to dissect the complexities of Platynereis circadian daily behavior, enhancing our understanding of the organism’s intricate patterns.

Manchester, England, United Kingdom

Research Areas: GPCR signalling, Visual and Non-Visual Photoreceptors, Mammalian cell culture, Tool development✔︎ Unraveled G-Protein signaling and spectral characterization of visual and non-visual opsins using cell-based second messenger assay, shedding light on intricate signaling mechanisms. ✔︎ Innovated with chimeric-opsin technology: Developed and utilized chimeric-opsin to dissect downstream signaling cascades, advancing the understanding of photoreceptor inhibitory signals.

Vienna, Austria

Research Areas: Biological clock, Photoreceptor biology, Genetic tool development, RNA biology, Proteomics✔︎ Co-led molecular method development workgroup: Guided the initiatives within the framework of ERC grant contributing to cutting-edge research methodologies.✔︎ Pioneered Advanced Genetic Techniques: Developed a comprehensive genetic toolkit including BAC-mediated transgenesis, conditional chemical induced-genetic ablation, TALEN, and CRISPR-mediated knockouts, enhancing genetic research capabilities.✔︎ Discovered Novel Photoreceptor: Identified novel peripheral visual photoreceptor r-opsin1, uncovering its potential involvement in mechanosensory non-visual functions, expanding understanding of Platynereis sensory mechanisms.✔︎ Provided Comprehensive Project Insights: Offered valuable insights throughout the project lifecycle, ensuring cohesive project development, and provided detailed reports to internal advisors and scientific committees.

Bengaluru, Karnataka, India

Research Areas: Protein Bioinformatics, Whole genome analysis, Insilico structure prediction, Data mining, Database management✔︎ Using genome-wide sequence analysis of Arabidopsis thaliana, identified novel Hsp chaperons and developed a systematic classification of all J-class related Hsp proteins.✔︎ Initiated, designed and developed the research project - HSPIR database resources for heat shock proteins.✔︎ Managed lab resources and project budget.

Doctor Of Philosophy - Phd, Molecular Biology, Grade 1, Excellent

Activities and Societies: Molecular Biology, Biochemistry, Genetics, Chronobiology, Photobiology, Molecular and Behavioural Neuroscience.

Master'S Project, Bioinformatics, Grade 1, Excellent

Thesis - Genome-wide and Structural analyses of J-class Heat shock protein family

Visiting Student, Bioengineering And Biomedical Engineering, Grade 1, Excellent

Thesis - An In silico and chromatographic analysis of Antidiabetic medicinal plant drugs

Master Of Science - Msc, Bioinformatics, Grade 1; Distinction; University Rank Holder

Bachelor Of Science - Bsc, Microbiology, Grade 1; Distinction, Best Outgoing Student Award

Project - Establishment of spirulina micro algae culture