Veli-Pekka Jaakola Email & Phone Number

Helsinki, Fi

Villigen, Aargau, Ch

https://leadxpro.com/

Zwijnaarde, Be

http://confotherapeutics.comProtein Science function head in a matrix-like project organization. Leadership/line-manager for team of >12 researchers. Team responsible for structural biology of active-state GPCR:G-protein:nanobody complexes to guide SBDD; GPCR and other protein tool antigen production for antibody/biologics discovery team. Responsible for single-domain antibody and Fc conjugate production, characterization and formulation. Solved several active-state “fragment-like” GPCR complex structures below 3 A resolution. Structural biology of biologics:receptor complexes. Supported generation on novel antibody biologics in several projects for in vivo studies.

Basel, Baselstadt, Ch

Lab head (GPCR biophysics and structural biology, Protein Science Group, Chemical Biology and Therapeutics Unit, NIBR Basel). http://postdoc.nibr.com/veli-pekka-jaakola.htmlDevelopment of recombinant GPCR protein production suite for structural biology and biophysics. Highlights: platform for GPCR protein scouting for biophysical screening assays to guide SBDD, novel GPCR structure solved with in-house ligands, functional nanobodies produced for GPCR xtallization and G-protein modulation, GPCR produced for successful DNA-encoded library screening, routine analytics for purified GPCR such as intact MS, protein-detergent concentration, nanoDSF, mobility in LCP and ligand binding; infrastructure for MPs: SONICC-UV, LCP-FRAP, TTP Labtech's Mosquito-LCP, DLS and MALS-SEC.

Oulu, Oulu, Fi

Adjunct Professor/Group Leader at the Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine (FBMM) , University of Oulu, Finland (http://www.oulu.fi/fbmm/)Projects: Adenosine A2A receptor and interactions with intracellular modulator proteins. Equilibrative nucleoside transporter 1 (ENT1).Mentored Ph.D. degrees (4); M.Sc./B.Sc. degrees (6)14 publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=jaakola+vp)Improvement on the department infrastructure: 2 x Rock-Imager Formulatrix protein crystallization imaging systems, Xantus and TTP Labtech's Mosquito-LCP Xtallization robots, MALS (Wyatt) – SEC (Shimadzu HPLC), DLS DynaPro Plate Reader, FluoroMax-4 spectrofluorometer

La Jolla, California, Us

Postdoctoral Research AssociateThe Stevens Laboratory (http://stevens.scripps.edu/)Joint Center for Innovative Membrane Protein Technologies (http://jcimpt.scripps.edu/)GPCRs; human adenosine receptors.

Macromolecular Structures Group (Adrian Goldman):PhD thesis:http://ethesis.helsinki.fi/julkaisut/bio/bioja/vk/jaakolaSetting up an automated crystallization system: http://www.biocenter.helsinki.fi/bi/xray/automation/Projects:Alpha-2-Adrenoceptors, Human Complement Factor, H+PPase, Bacteriorhodopsin mutants, Lactoglobulins

Turku, Varsinais-Suomi, Fi

Macromolecular X-ray Crystallography Group (Adrian Goldman)

Oulu, Oulu, Fi

Experimental part for pro gradu (MSc) thesis (6 months)http://www.oulu.fi/english/http://www.kajaaninyliopistokeskus.oulu.fi/bio/Laboratory_of_Biotechnology.htm

Laboratory assistant in lanthanide labeling laboratoryExperimental part for bachelor of engineering work (1995-1996)

Turku, -, Fi

Part time work

Master Of Business Administration - Mba, International Business Management

Opettajan Pedagogiset Opinnot · Pedagogical Studies For Teachers (60 Credits)

Phd, Biochemistry

Msc, Biotechnology; Cell And Molecular Biology

Beng, Biotechnology, Molecular Biology