Vu Thai Email & Phone Number

San Rafael, CA, US

Novato, California, US

Novato, California, US

Leverkusen, North Rhine-Westphalia, DE

Leverkusen, North Rhine-Westphalia, DE

Leverkusen, North Rhine-Westphalia, DE

• Early Stage Development of Downstream Process (DSP) for therapeutic biomolecule
• Successfully developed and optimized Phase I DSP. o Planned and executed bench scale resin screening experiments including purification and analytical assays. o Developed and optimized multi-column purification scheme.
• Lead and executed bench-scale experiments to evaluate and optimize process changes to DSP.
• Lead 4x pilot scale development runs to assess process scale up and comparability. Generate material for toxicology and drug product stability studies.
• Optimized operation of pilot scale runs to reduce process time.
• Interim Downstream lead and representative on technical development team. o Supervise activities of 5-6 member team. o Coordinate activities between cross-functional groups (Upstream, Downstream, AD, and FFD) to ensure.

Santa Cruz, CA, US

• My research is focused on understanding the molecular mechanisms that coordinate cell growth and cell size. Proper regulation of PP2A-Cdc55 at the G2/M cell size check point is important for entry into mitosis. However.
• Immunoaffinity purified PP2A-Cdc55 from S. cerevisiae for mass spect. mapping of in vivo phosphorylation site.
• Generated strains containing non-phosphorylatable mutants of PP2A-Cdc55 to assess the in vivo relevance of the phosphorylation sites.
• Devised expression and purification protocols for several recombinant proteins involved in the proposed signaling pathway. Obtained mg - gram quantities of target proteins from E.coli and µg quantities from yeast.
• Developed in vitro kinase and phosphatase assays to show that PKC1 and PP2A-Cdc55 act on each other.
• Mentored 4 undergrad and 6 grad students in scientific protocols and assisted in supervising their research.

Waltham, MA, US

Structure, Dynamics, and Stability of Extremozymes.Utilized X-ray crystallography, NMR spectroscopy, and other biophysical techniques to characterize and compare enzymes from extremophilic bacteria to their mesophilic homologs.

Whittier, CA, US

Research was focused on purifying and characterizing the fibrinolytic enzyme Apcfib from the venom of the Florida cottonmouth.

Davis, California, US

Awarded a Summer Undergraduate Research Fellowship (S.U.R.F.). Research was focused on characterizing how different factors affect vesicle production.

Ph.D., Biochemistry/Biophysics

Bachelor Of Arts (B.A.), Chemistry/Biochemistry