• Using CRISPR-Cas9 technology to generate a transgenic mouse model which carrying human gene to evaluate a cancer therapy before applying for clinical trials.• Exploring the combination of cytokines and checkpoint inhibitors as a potential therapy in pancreatic cancer treatment.• Developing of a COVID-19 vaccine and evaluating its safety & efficacy using biological methods & animal models.• Analyzing immune cells in cancer models to study how radiation affects the immune system, with the goal of developing a novel immunotherapy-based approach to radiotherapy.

• Studying the feasibility of using Salmonella-based therapy to deliver shRNA to treat pancreatic cancer and colorectal cancer using mouse models.

• Genetical engineering Salmonella and E. coli to become specific molecular probes for Cancer Imaging and Therapy.• Optimizing gene expression of bacteria using remote-controllable promoters to improve the safety issue when applying in vivo as a toxin gene delivery.