Don Walker Email and Phone Number
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Expertise in preclinical drug metabolism and pharmacokinetics as applied to drug discovery and development gained through 24 years experience with Pfizer Global Research and Development (UK) in various management roles and senior scientific roles in departments of Drug Metabolism and Pharmacokinetics, Dynamics and Metabolism. Membership and leadership of global Pfizer teams involved in harmonisation of scientific best practices and maintaining the organisation at the forefront of scientific and technological innovation. Line representative for many internal project development programs (including sildenafil for erectile dysfunction and pulmonary hypertension, dofetilide for cardiac arrhythmia and maraviroc for HIV) and licensing evaluations with external companies. Contributing author to global regulatory submission dossiers and query responses in areas of scientific expertise for sildenafil, dofetilide, maraviroc and voriconazole. Industry and academic tutor in fields of drug metabolism, pharmacokinetics, toxicokinetics and physicochemistry as applied to drug discovery and author of over 50 scientific papers and book chapters.Specialties: Preclinical drug metabolism and pharmacokinetics (PK) as applied to drug discovery & development.Preparation of PK and metabolism sections for regulatory summaries for global submissions.Application of physicochemical information to rational drug design.Management of drug discovery, preclinical development and bioanalytical (including GLP) functional groups.Liaison with pharmacology, toxicology, clinical pharmacology and regulatory experts in support of drug development & registrations.
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Network PartnerThe Research Network Mar 2013 - PresentCanterbury, United Kingdom -
Freelance Drug Metabolism And Pharmacokinetic ExpertNo Company Mar 2010 - PresentExpertise in preclinical drug metabolism and pharmacokinetics in support of drug discovery and development. Established author of scientific papers and regulatory submission documentation. -
Research Fellow (Pharmacokinetics, Dynamics And Metabolism)Pfizer 2008 - 2010Scientific Leader for Europe for Development Strategies Group within Pharmacokinetics, Dynamics and Metabolism. Group has responsibility for ensuring high quality science in support of the PGRD development portfolio and proactive engagement with regulatory bodies to align our scientific strategy and facilitate drug registrations. -
Senior Director (Pharmacokinetics, Dynamics And Metabolism)Pfizer 2002 - 2008Group Manager for DMPK Groups for Preclinical Development and BioanalysisLed Preclinical Development Group between 2002 and 2005, managing a group of ~12 scientists involved in studying metabolism and disposition of drug development candidates in animal species and man. Member of global discipline board to establish best practices, advance metabolism and pharmacokinetic science and ensure awareness of regulatory expectations.Led bioanalytical group between 2005 and 2008, managing group of ~ 30 scientists involved in bioanalytical work to support drug discovery and development programs. Responsible for GLP bioanalytical function in support of toxicokinetic sample analysis and PK from early clinical studies. Member of departmental management team and global discipline board for DMPK science.
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Research Scientist (Drug Metabolism)Pfizer 1986 - 2002Laboratory scientist involved in the generation of in vivo and in vitro metabolism and pharmacokinetic data from preclinical and clinical studies. Developed fit for purpose bioanalytical assays fro drug discovery and drug development programs using HPLC and radioimmunoassay techniques. Interpretation of data using pharmacokinetic analysis and member of drug discovery and drug development project teams as departmental representative. Development of role included growing team leader responsibilities involving training and development of junior scientists.
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Research AssociateMedical Research Council 1984 - 1985Working in Developmental Neurobiology Unit. Research involving the analysis of various endogenous markers that may be involved in Down's Syndrome using techniques including TLC and GC -
Research AssistantUniversity College London 1981 - 1984Research Assistant in group conductung research into Inborn Errors of Metabolism. Work involved analysis of urine, plasma and tissues samples for organic and amino acids for the detection of inborn errors of metabolism. Techniques used included liquid-liquid extraction, solid phase extraction, TLC, GC and HPLC (amino acid analyser).
Don Walker Skills
Don Walker Education Details
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Biochemistry With Chemistry
Frequently Asked Questions about Don Walker
What company does Don Walker work for?
Don Walker works for The Research Network
What is Don Walker's role at the current company?
Don Walker's current role is Consultant in Drug Metabolism and Pharmacokinetics.
What is Don Walker's email address?
Don Walker's email address is do****@****-fc.com
What schools did Don Walker attend?
Don Walker attended University Of London.
What skills is Don Walker known for?
Don Walker has skills like Drug Metabolism, Drug Discovery, Pharmacokinetics, Drug Development, Dmpk, Bioanalysis, Pharmacology, Glp, Adme, Toxicology, In Vitro, Clinical Research.
Who are Don Walker's colleagues?
Don Walker's colleagues are Decondia Mixon, Andrew Mcelroy, Reece Speaeman, Graham Maw, Rebecca Myatt, David Tuffin, Dermott O'callaghan.
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