Focusing on nucleic acid drug discovery, covering siRNA, linear mRNA, saRNA, and circRNA.My main goal to design best constructs for our nucleic acid platform.I also lead a team of 20 scientists to develop other platforms, including cell Biology, mRNA delivery system(LNP), and siRNA delivery system (GalNac).

mRNA vaccine development and antibody discovery

RNA targeted small molecules drug discovery

RNA-targeted drug discovery focusing on microRNAOligo synthesis using MerMade12 synthesizerOligo purification (RNA/DNA) using HPLC, AKTA, SDS-PAGE sequencing gel.

Molecular cloning, recombinant protein expression/production, post-translational modification of protein using LC-MS, and cell culture

Research Area: non-coding RNAs and Protein/RNA interactions:Structural Biology in NMR and X-rayProtein Engineering and molecular cloningT7 polymerase preparation for RNA synthesis.In vitro transcription (IVT) for RNA production. Purification of RNA using PAGE gel and ElutrapDocking and computational modeling