Bioengineer
Eth, Swiss Federal Institute Of Technology, Zurich
http://www.ncbi.nlm.nih.gov/pubmed?term=Little+WC+Vogel+VI have three older brothers who encouraged me - as I was considering what to do in college - to aim for an engineering degree (of any kind). The basic thought there was I could learn Liberal Arts on the side (to be "well-rounded", of course), but an engineering degree had significantly higher market value. :) I've always appreciated that advice. So, indeed, I took my love for biology and wondered into a nanotechnology lab at the University of Washington and learned everything I could from the grad students there. The Bioengineering Department at that point only had a graduate program, but there was a small, stubborn set of us undergrads that wanted to hang out in BioE so they let us in, giving us "Interdisciplinary Engineering" bachelors degrees until we went off to medical school or got MS/PhDs from them. I ended up getting my Masters in Bioengineering there and followed my advisor to Zurich to finish my PhD. For the better part of a decade, as an undergraduate and graduate student, I researched a connective tissue protein called Fibronectin. It circulates around in our blood serum (in soluble form) until it's woven by cells into our Extracellular Matrix (ECM) when tissue growth & regeneration is needed. In it's insoluble, fibrillar form in the ECM, Fibronectin serves a variety of important biophysical functions. I focused on an area of science called Mechanotransduction, which, as Wikipedia will correctly tell you, "refers to the many mechanisms by which cells convert mechanical stimulus into chemical activity." In my case, I worked a ton with Fibroblast cells in tissue culture and researched how they used mechanical force to pull on Fibronectin to do things like reveal cryptic binding sites. Other cells see these new binding sites, bind to them, and activate signaling pathways. Published papers: http://www.ncbi.nlm.nih.gov/pubmed?term=Little+WC+Vogel+V