William Duddy Email & Phone Number

I am co-lead of the Duguez neuromuscular lab (https://www.duguezlab.org/), situated in the Personalised Medicine Centre of Ulster University's School of Medicine. We develop therapies and diagnostic tools for neuromuscular and neurodegenerative pathologies.Previously, as project leader in bioinformatics at the Center of Research in Myology, Paris, I developed and applied data mining and systems biology approaches to muscle disease, especially for functional analyses of omics data. Some of my tools are found here (https://www.sys-myo.com/). I’ve also been involved in the in silico design of exon skipping oligonucleotides for genetic diseases such as Duchenne muscular dystrophy (DMD), and of novel truncated dystrophin proteins for DMD gene therapy. My PhD was on computational analyses of protein and protein::ligand interaction geometry, during which I learned various large data analytical techniques and programming. I then did wet-lab systems biology research at the Department of Integrative Systems Biology at Children's National Medical Center, Washington DC, where I ran transcriptome, proteome, and secretome analyses on cell and mouse models of muscle disease, as well as studying muscle stem cell behaviour. In neuromuscular disorders I am motivated by my personal background, having had a brother with Duchenne MD.

Listed skills include Data Analysis, Systems Biology, Bioinformatics, Molecular Biology, and 1 others.

• Lecturer In Stratified Medicine

  Northern Ireland Center For Stratified Medicine University Of Ulster

  Londonderry, Gb