Wen-Ching C. Email and Phone Number

- Lead the development of an early detection panel using circulating tumor methylated DNA (ctmDNA).- Contribute to pipeline optimization, performance improvement, and code reviews for applications developed in Oncology (solid cancers, liquid biopsy) products using Whole-Genome Sequencing (WGS) data.- Oversee the development of bioinformatics algorithms and pipelines for applications supporting Organ Health products using whole transcriptome (mRNAs) and small non-coding RNA (sncRNAs) sequencing data.

Oncology product development: Whole-Genome/-Exome Sequencing (WGS/WES) analysis, Microsatellite Instability (MSI) analysis, Primer Design of large dual primers/human viral genomes, Copy Number analysis in personalized panel design.

Center for Research Informatics- Develop and leverage computational methods to align (BWA, STAR), detect (DESeq2, limma, MACS2, DSS2), annotate (VEP, snpEff), and discover biological functions (Gene Ontology, KEGG) from NGS data and other complex multi-omics data (GDC/TCGA, dbSNP, COSMIC, 1000 Genomes).- Conduct variant-calling analyses (GATK4/Mutect2, VarScan2) and manipulations (SAMtools, Picard) using whole exome/genome sequencing data in human, mouse, and bacteria.- Contribute to the development of bioinformatics pipelines (Nextflow, Conda) running in distribution systems (HPC) for data analysis, integration, and management.Skill Badges:https://www.credly.com/badges/2da8dc4b-d90a-405d-ba15-6b7623723c49/public_url