Wesley Concepcion Email & Phone Number

Gothenburg, Västra Götaland County, Sweden

Port Ludlow, Washington, United States

Fjällbacka, Swe

Boston, Massachusetts, United States

Woburn, Ma

Biophysical and Chemistry Group, Analytical Development, Gene Therapy, Ultragenyx Pharmaceuticals, Woburn, MA• Developing early and late stage analytical methods for multiple AAV8 and AAV9 programs:o Developing an empty/full method by Anion Exchange Chromatography to provide high throughput, QC friendly, alternative Phase 2 method for Empty/Full Capsids. o Developing a platform, release method for sub-visible particles using background membrane imaging (BMI), fulfilling an FDA requirement for sub-visible particulate contamination.o Developing a method for SEC-MALS to quantify platform CQA’s: aggregation, particle titer, and empty-full. o Developed a phase 2 total particle titer method by Multi-Angle Light Scattering (Zetasizer Ultra) for in-process testing, currently yielding lower %CV’s than other titer methods. o Increased AUC throughput 2-fold by optimizing absorbance detection, spin speed, and cell cleaning procedure. Ultimately my changes are improving efficiency through turnaround time.• Increased throughput of in-process AUC samples by establishing a working relationship with CRO. • Facilitated qualified method transfer to QC team.• Assisted in set up and organization of a new 3,850 sqft analytical development lab space; including leading the evaluation and implementation of two Waters Alliance HPLC’s, Malvern’s Zetasizer Ultra, Waters BioAccord Mass Spec, Wyatt MALS (DAWN Heleos II, Optilab t-rEX), ProteinSimple CE-SDS (Maurice), HaloLabs Horizon; allowing for a dynamic and efficient working environment for all groups.

Cambridge, Massachusettes

Supported process development and quality control teams with biophysical characterization testing for AAV particle titer, purity, and empty/full ratio; increasing throughput and decreasing data turn-around times.

Moscow, Id

• Developed and implemented quantitative LC-MS/MS analytical methods for small molecule DMPK studies. • Validated LC-MS/MS analytical methods, analyzed study samples, generated data and reports, all in accordance with SOPs, GXPs, and FDA regulations and guidelines. • Fostered working relationships with multiple clients, ensuring timely delivery of data and reports, increasing client retention and company profits. • Maintained laboratory equipment, including troubleshooting and repair of Shimadzu HPLC systems and AB Sciex Triple Quad MS (4000, 5500, 6500, 6500+) systems.

Moscow, Idaho

Perform routine facility maintenance and inspections. Perform PM/PQ on LC-MS/MS systems.QC review of sample analysis and validation data. Prepare reagents and solutions for laboratory operations, including standards and solvent mixtures for use in LC-MS/MS applications.

Seattle

Kent, Washington

Assisted lead installer with demolition, preparation, and installation of commercial flooring including LVT, carpet tile, ceramic tile, and VCT.

Pullman, Wa

Starting Punter under Head Coach Mike Leach for three consecutive seasons. Walked-on to the Football Team as a freshman. Dedicated 40+ hours per week before and after classes for three years towards football activities including workouts, film study, team meetings, and practices.

Snoqualmie Pass, Wa

Individual and assistant instructor for students ages 6-50+. Implement learning progression to fit the learning style of the student. Successfully teach safety and skill on the mountain. Achieved Level 1 PSIA/AASI ranking.

Tukwila, Wa

Master Of Science - Ms, Physics - Complex Adaptive Systems

Master Thesis: Developing a transformer model using a quantum kernel as the self-attention mechanism.

Bachelor’S Degree, Biochemistry, Biophysics And Molecular Biology

Activities and Societies: Washington State NCAA Football Team, Lambda Chi Alpha FraternityMinoring in Chemistry, Math, and Engineering

High School, Pre-Medicine/Pre-Medical Studies

Activities and Societies: 4 Year Football Letterman, 2 Year Soccer Letterman, 2 Year Swimming & Diving Letterman, Leadership Team, Link.

Data Science, Pass

Used Python to develop machine learning systems to make informed decisions about a given project.