Wesley Mckeithan work email
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Wesley Mckeithan personal email
Wesley Mckeithan is a Senior Scientist at NewLimit at NewLimit.
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Senior ScientistNewlimit Oct 2022 - PresentSouth San Francisco, California, Us -
Scientist IiMaze Therapeutics Dec 2020 - Oct 2022South San Francisco, California, Us -
Postdoctoral ScholarUniversity Of California, San Francisco Jul 2018 - Dec 2020San Francisco, California, UsPostdoctoral Fellow, Wendell Lim Lab, Department of Cellular and Molecular Pharmacology, -
Postdoctoral ScholarStanford University School Of Medicine Mar 2018 - Jul 2018Palo Alto, Ca, Us -
Life Science Research ProfessionalStanford University School Of Medicine Feb 2016 - Mar 2018Palo Alto, Ca, Us- Co-developed a high-throughput optical assay to quantify cardiomyocyte motion in 384 well plates and characterized the effect of small molecule modulators of cardiomyocyte contractility.- Utilized the cardiomyocyte motion assay to screen a small library of tyrosine kinase inhibitors and calculated a cardiac safety index that predicted the clinical risk of cardiotoxicity for patients.
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Phd StudentSanford Burnham Prebys Medical Discovery Institute Sep 2013 - Jan 2018La Jolla, Ca, Us- Dissertation title: “Reengineering an Antiarrhythmic with Human Pluripotent Stem Cells.”- Established an automated platform to quantify action potential kinetics of induced pluripotent stem cell derived cardiomyocytes (hiPSC-CM) capable of screening 10,000+ wells in 384 well plates.- Developed a hiPSC-CM model of congenital long QT syndrome type 3 to screen analogues of mexiletine and generate a structure activity relationship that resulted in novel small molecule drug candidates with improved potency and selectivity for the late sodium current.- Discovered a novel gene regulatory network controlling the initiation of cardiogenesis using -
Lab Assistant IiUniversity Of California, San Diego - Jacobs School Of Engineering Feb 2013 - Sep 2013La Jolla, Ca, UsFormulated a cell culture media that improved physiological properties of hiPSC-CMs in functional assays measuring metabolic flux, calcium handling, electrophysiology, and force generation. -
Research Technician IiSanford|Burnham Medical Research Institute Jun 2009 - Feb 2013La Jolla, Ca, Us- Developed assays suitable for performing high content/high-throughput functional screening of RNA libraries utilizing the kinetic image cytometry platform- Identified specific microRNA families which regulate cell fate decision during embryogenesis by high throughput screening and systems biology- Proficient in high-content/high-throughput screening and imaging techniques (fluid handling robotics, automated microscopy) as well as image segmentation and analysis software (Cyteseer)- Expert in cell culture and transfection of mouse and human embryonic stem cells, human IPSC-derived cardiomyocytes, cardiac fibroblasts, HEK 293, HeLa- Highly skilled in molecular biology techniques: Cloning, RNA extraction, cDNA synthesis, qPCR, Western blot, immunostaining, in situ hybridization- Well versed in the concepts and principles of stem cell biology, regenerative medicine, cardiac electrophysiology, mouse and Xenopus laevis embryology
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Senior Sales AdvisorVector Marketing Jan 2007 - Aug 2007Olean, Ny, Us- Member of the Presidential Sales Club- Winner of the “Fast-start” contest selling $10,000 of Cutco Brand kitchen knives in 10 days
Wesley Mckeithan Education Details
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Sanford Burnham Prebys Medical Discovery Institute Graduate School Of Biomedical SciencesBiomedical Sciences -
University Of San DiegoBiochemistry
Frequently Asked Questions about Wesley Mckeithan
What company does Wesley Mckeithan work for?
Wesley Mckeithan works for Newlimit
What is Wesley Mckeithan's role at the current company?
Wesley Mckeithan's current role is Senior Scientist at NewLimit.
What is Wesley Mckeithan's email address?
Wesley Mckeithan's email address is wm****@****ord.edu
What schools did Wesley Mckeithan attend?
Wesley Mckeithan attended Sanford Burnham Prebys Medical Discovery Institute Graduate School Of Biomedical Sciences, University Of San Diego.
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