Wesley Leoricy Marques Email & Phone Number

Basel, BS, CH

Berna, Suíça

Berna, Suíça

• Luya Foods was founded in 2021.
• Promoted within one year for exceeding goals and supporting company management.
• Experience of driving R&D teams or projects to achieve commercial objectives.
• Lead projects on liquid and solid-state fermentation of industrial side-streams for food production.
• Responsible for the fermentation quality at the production site and for scale-up efforts.
• Utilized Machine Learning for predicting fermentation outcomes based on bioreactor data.

Tours E Região

• Developed and executed the strategy of the Microbial Metabolism Center of Expertise.
• Led projects on microbial fermentation using bench-top bioreactors and employed Machine Learning models for predictive analytics.
• Designed new laboratory installations for high-throughput screening and automation.
• Managed a team of researchers and oversaw on-site analytics facility.
• Managed projects involving strain construction, fermentation, biochemistry, systems biology (genome-scale metabolic models) and machine learning.
• Fostered cross-functional collaborations with internal and external partners.

Cambridge, MA

• Prather's Lab (Chemical. Eng) https://prathergroup.mit.edu
• Engineered the metabolism for saccharic acid production in Saccharomyces cerevisiae and Escherichia coli resulting in published research.
• Conducted batch fermentations and screened enzyme homologues (myo-inositol oxygenase) to increase product formation.
• Received the MIT Postdoc award (10’000 USD) for project proposal on E. coli metabolic engineering aimed at decoupling growth from product formation.
• Worked in close cooperation with and partially sponsored by industry (Kalion, Inc).

Delft

• Engineered the sugar metabolism of Saccharomyces cerevisiae, leading to a substantial increase in ATP yield. This optimized strain serves as an enhanced chassis for product synthesis in low or non-aerated bioreactors.
• Performed quantitative physiological characterization in bioreactors (chemostats) and evolution (sequential batch reactors and accelerostat) of yeast strains.
• Invented a CRISPR/Cas9 multiplexing technology for the deletion of entire gene families in yeast in one go. Results published.
• Conducted enzymatic assays of key enzymes from the central carbon metabolism of yeast.
• Presented results in multiple international conferences.
• Published a highly regarded review on sucrose metabolism in yeast, which ranked as the top-first read paper for three consecutive years in FEMS Yeast Research.

Mogi Guaçu E Região, Brasil

• Investigated the feasibility of replacing the classical tree-breeding program by a DNA-sequencing method (GWS). The company is now using GWS in their breeding pipeline.
• Produced transgenic plants to study cellulose biosynthesis.
• In depth molecular biology training: cloning, real-time PCR, norther-blot, bioinformatics

Postdoc Industrial Microbiology In The Chemical Eng. Dpto.

• Prather's Lab (Chemical. Eng) https://prathergroup.mit.edu • Optimized the biosynthetic route for saccharic acid production in.

Phd In Industrial Microbiology

Dual degree between the Delft University of Technology-TUDelft (Biotechnology Dept.) and the University of Campinas-Unicamp (School of.

Master Of Science (Msc) - Biotecnhology

University of São Paulo-USP (Department of Chemical Engineering) with six months internship at TUDelft (The Netherlands) Thesis.

Bachelor Of Science - Bs, Molecular Biology

Thesis: "Increasing plant cellulose deposition aimed at improving wood quality for paper and pulp production". Advisor: Gonçalo Pereira.