William D. Shrader Email and Phone Number
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Experienced leader of R&D teams in neurodegeneration, inflammation, cardiovascular disease and oncology, resulting in 4 drugs advancing through phase 2 clinical trials in ALS, Parkinson’s disease, Pancreatic cancer, Rett syndrome, Friedreich’s ataxia and Leigh syndrome.Seasoned executive in creating productive co-development drug partnerships and business development in/out-licensing activities.Highlights:• Invented and developed EPI-589 for adult neurodegenerative diseases, currently in phase II clinical studies for amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). Licensed to Sumitomo in one of the 10 largest deals of that year.• Discovered and developed the 15-lipoxygenase inhibitor, EPI-743, which was recently sold to PTC Therapeutics. Currently in Phase II for pediatric orphan mitochondrial disease (Friedreich’s Ataxia, Leigh Syndrome) and Parkinson’s disease.• Invented and developed the factor VIIa/Tissue Factor inhibitor PCI-27483. Licensed to AbbVie and is currently in phase II for Pancreatic cancer.A medicinal chemist with an extensive track record in integrating multiple disciplines (medicinal chemistry, enzymology, ADME, PK/PD, in-vitro and in-vivo pharmacology, biology, toxicology, process chemistry, clinical biomarkers/translation, regulatory and intellectual property) to rapidly advance drug discovery and development programs into clinical trials.Innovator of translational biomarkers of neuroinflammation, in ALS and PD clinical trials to demonstrate drug/target engagement.Author of 30 peer-reviewed scientific publications and inventor of 21 issued US patents.
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Cso And CofounderAcurex BiosciencesSan Carlos, Ca, Us
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Cso And CofounderAcurex Biosciences Apr 2024 - PresentSan Carlos, Ca, Us -
Founder And Ceo/CsoAcurex Therapeutics Corporation Jan 2020 - Jul 2024
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FellowBioelectron Technology Corporation Jan 2017 - Jul 2019
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Senior Vice President, InnovationEdison Pharmaceuticals, Inc. Feb 2010 - Oct 2017
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Vice President Of Research And DevelopmentEdison Pharmaceuticals, Inc. Mar 2006 - Jan 2010
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Associate DirectorCelera Genomics 2001 - 2006 -
Group LeaderArris Pharmaceuticals 1996 - 1997
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ChemistAbbott Laboratories 1986 - 1988Abbott Park, Illinois, Us
William D. Shrader Skills
William D. Shrader Education Details
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CaltechBio-Organic Chemistry -
University Of California, BerkeleyOrganic Chemistry
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University Of Illinois Urbana-ChampaignChemistry
Frequently Asked Questions about William D. Shrader
What company does William D. Shrader work for?
William D. Shrader works for Acurex Biosciences
What is William D. Shrader's role at the current company?
William D. Shrader's current role is CSO and Cofounder.
What is William D. Shrader's email address?
William D. Shrader's email address is bs****@****rma.com
What is William D. Shrader's direct phone number?
William D. Shrader's direct phone number is +165034*****
What schools did William D. Shrader attend?
William D. Shrader attended Caltech, University Of California, Berkeley, University Of Illinois Urbana-Champaign.
What skills is William D. Shrader known for?
William D. Shrader has skills like Chemistry, Life Sciences, Pharmaceuticals, Drug Discovery, Analytical Chemistry, Medicinal Chemistry, R&d, Biopharmaceuticals, Biochemistry, Biotechnology, Cro, Clinical Development.
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