William Hewitt Email and Phone Number
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William Hewitt is a Senior Scientific Lead at Eli Lilly and Company. He possess expertise in synthetic organic chemistry, nmr spectroscopy, ir spectroscopy, gas chromatography, hrms and 29 more skills.
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Senior Scientific LeadEli Lilly And CompanyBoulder, Co, Us
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Senior Scientific LeadLoxo Oncology At Lilly Jan 2023 - PresentStamford, Ct, Us -
Principal Scientist, Medicinal ChemistryLoxo Oncology At Lilly Sep 2021 - Dec 2022Stamford, Ct, Us -
Senior Scientist, Medicinal ChemistryLoxo Oncology At Lilly Jan 2020 - Sep 2021Stamford, Ct, Us -
Associate Medicinal ChemistLoxo Oncology At Lilly Jun 2018 - Jan 2020Stamford, Ct, Us -
Postdoctoral FellowNational Cancer Institute (Nci) Jan 2015 - May 2018Bethesda, Md, UsLead a cross-disciplinary collaborative team toward the investigation of a novel allosteric binding site which regulates the E2 enzyme of the SUMOylation pathway (Ubc9), presenting a new approach to chemical regulation of an "undruggable" class of enzymes. Currently working to synthesize a class of natural products which selectively inhibit the SUMO E2 enzyme as part of a collaborative team. -
Graduate Student Researcher - Lokey GroupUc Santa Cruz Apr 2012 - Dec 2014Santa Cruz, Ca, UsUtilizing solid-phase peptide synthesis to develop new methodology for direct permeability analysis of complex synthetic libraries of cyclic peptides for the rapid discovery of membrane permeable cyclic peptides. This work was applied to the discovery of several new cyclic hexapeptides with measurable cell permeability, and has recently been applied to investigate the size limitation for large cell-permeable macrocycles. -
Graduate Student Resesarcher - Konopelski GroupUc Santa Cruz Sep 2009 - Apr 2012Santa Cruz, Ca, UsStreamlined synthesis of advanced synthetic intermediates to improve efficiency and to make amenable for scale-up. Successfully synthesized several strained bicyclic β-lactam ring systems for future use as chiral directing scaffolds in natural product synthesis. Synthesized an intermediate of a novel analogue of salinosporamide A, a natural product currently in clinical trials for treatment of multiple myeloma. -
Research AssistantSupergens May 2008 - Aug 2009Synthesized library of ~25 small molecules to investigate structure-activity relationship against kinase targets and to optimize inhibitory activity. Performed scale up synthesis of selected compounds for in vivo investigations.
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Undergraduate ResearcherUniversity Of Utah Aug 2007 - May 2008Salt Lake City, Utah, UsSynthesized manganese-based organometallic complexes to investigate carbon-fluorine bond activation. Analyzed synthetic complexes via x-ray crystallography and NMR to characterize extent of bond activation by bond length. -
Research Intern / Lab TechnicianCelanese Jan 2007 - Aug 2007Irving, Texas, UsOptimized workflow for use of GC instrumental analysis of crude reactor samples and quantified amount of time needed between instrument maintenances. -
Process Chemist InternCelanese May 2006 - Aug 2006Irving, Texas, UsDeveloped new method of analyzing headspace gas in critical points of the industrial plant line.
William Hewitt Skills
William Hewitt Education Details
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University Of California, Santa CruzOrganic Chemistry -
University Of UtahChemistry
Frequently Asked Questions about William Hewitt
What company does William Hewitt work for?
William Hewitt works for Eli Lilly And Company
What is William Hewitt's role at the current company?
William Hewitt's current role is Senior Scientific Lead.
What is William Hewitt's email address?
William Hewitt's email address is wi****@****ail.com
What schools did William Hewitt attend?
William Hewitt attended University Of California, Santa Cruz, University Of Utah.
What are some of William Hewitt's interests?
William Hewitt has interest in Children, Education, Science And Technology, Disaster And Humanitarian Relief, Arts And Culture.
What skills is William Hewitt known for?
William Hewitt has skills like Synthetic Organic Chemistry, Nmr Spectroscopy, Ir Spectroscopy, Gas Chromatography, Hrms, Tlc, Flash Chromatography, Solid Phase Synthesis, Hplc, Lcms, Optical Rotation, Melting Point.
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