William Smith Ph. D. Email & Phone Number

Mebane, Nc, Us

Teda, Tianjin, Cn

Provide technical guidance and scientific leadership to China-based process chemistry teams. Expand Asymchem’s capabilities in areas including peptide and oligonucleotide chemistry, enzyme catalysis, flow chemistry, electrochemistry, and non-precious metal catalysis. Identify possible applications on internal Asymchem and customer projects. Streamline and strengthen company policies and procedures Represent Asymchem technology development outside the company as needed, for example in . Presentations to customers, scientific publications, or technical presentations to professional societies.

Kansas City, Mo, Us

Kansas City, Mo, Us

Manage a group of 6 scientists, responsible for executing commercial and government synthesis projects. Prepare quotations in response to client request for proposals. Prepare successful grant proposals, including budgets and Gantt charts for deliverables. Converted a kilo-lab to cGMP lab. In support of setting up cGMP lab, authored SOPs, Quality Agreements and Master Validation Plan. Responsible for process research development safety analysis and risk assessment. Responsible for staff training compliance. Created novel synthesis processes for customers, resulting in reduced cost and development time and higher yields. Developed innovative routes for synthesis of advanced pharmaceutical intermediates.

Nanjing, Jiangsu, Cn

Responsible for expanding the client base while improving relationships within existing accounts. Coordinate with US and European clients on all aspects of the contract process, including execution of CDA/MSA and submission of quotations. Advise and communicate with production scientists in China and with clients on strategic and technical issues of projects to ensure timely delivery of final product.Maintain active communication with clients and serve as primary liaison between stakeholders to drive project success. Contribute on marketing strategy initiatives and corporate communications messaging. Coordinated revenue verification with clients to fulfil requirement for Chinese public offering. Developed GMP SOPs for Chinese manufacturing facilities.

East Rutherford, New Jersey, Us

Conceptualized and implemented new route development that resulted in large savings and quicker synthesis of product for our customers. Responsible for customer quotes, safety analysis using reaction calorimetry, writing batch records and standard operating procedures. Reaction optimization using statistical analysis, parallel experimentation and design of experiment. Scale up to 500 gallons under cGMP guidelines. Produced synthetic development and validation reports and synthetic sections in IND and NDA filings. Managed between 2-6 external projects valued at 3 million dollars at any given time. Directed the work of 3-6 Ph.D. chemists. Other duties included chairing the internal chemistry meetings.

Brentford, Middlesex, Gb

New route development. Reaction optimization using statistical analysis, parallel experimentation and design of experiment. API crystallization and characterization using IR, TGA, DSC, microscopy and powder and Scale up to 500 gallons under GMP guidelines. Managed external projects. Other duties included chairing external speaker committee and coordinator for undergraduate scholar and mentoring program.

Indianapolis, Indiana, Us

Research in the area of Cardiovascular Research on therapeutic strategies targeting restenosis and pulmonary inflammation. Notable contributions included extending synthetic usefulness of an existing method for the synthesis of diaryl ethers and discovery of a new method for the synthesis of N-aryl indoles. Duties included the design and synthesis of novel heterocycles, thorough literature searches, laboratory and equipment maintenance, and molecular modeling using CATALYST, QUANTA, CHARMm, Macro Model, CUSP, and Spartan.

Ph. D., Chemistry

Ba, Chemistry

Education record

Education record

Education record

Education record