Scientist with specific expertise in metabolic and inflammatory diseases.I am currently a postdoctoral research scientist across the Harvard Medical School/ Brigham and Women's Hospital and Trinity College Dublin working on human metabolic and inflammatory diseases, with specific focus on adipose tissues and liver in the context of obesity and metabolic diseases. I have been characterising the cause of metabolic syndrome in obesity by conducting a clinical trial on bariatric surgery patients. This research investigated adipose tissues (subcutaneous and visceral), liver, and blood from patients for multi-omic assessment (RNA-seq, single cell RNA-seq), multi-colour flow cytometry, ex vivo tissue and cell culture, and microscopy. These data aim to identify potential underlying molecules and pathways that either predispose or protect certain individuals with obesity from developing metabolic disease(s) for downstream targetting and to aid in developing strategies for more timely surgical intervention for those individuals at-risk of developing such diseases.During this postdoctoral work I am also working on creating an 'atlas' of human adipose tissues by collecting multiple adipose tissue biopsies from various depots in patients undergoing surgery. Utilising a range of high-end techniques (RNA-seq, single cell RNA-seq, multi-colour flow cytometry, ex vivo tissue functional assessments), we hope to gain a deeper understanding of adipose tissue depots in humans that have previously been understudied, which will offer insights into their roles in immunometabolic diseases.I have also worked on developing a means of optically clearing various murine tissues for 3D confocal microscopy in order to understand the role of the immune system in tissue innervation.Previously, my PhD work was undertaken in Bath, UK and Toulouse, France with the European Space Agency to understand the impact of physical inactivity, ageing and nutrition on adipose, muscle, and systemic inflammation and metabolism. This work used the ground-based space flight analogue of head-down bed rest to assess the impact of long-term physical inactivity on adipose tissue inflammation and metabolism. I also conducted a clinical trial to assess the impact of ageing on adipose tissue and skeletal muscle inflammation and metabolism by comparing metabolic tissues in matched older and younger individuals. Both of these studies employed a range of techniques including multi-colour flow cytometry, RNA-seq, metabolic testing, ex vivo tissue culture, microscopy, adipocyte stimulations, and proteomics.