Tyler Winick Email and Phone Number
menlo park, california, united states
Tyler Winick's Location
Palo Alto, California, United States, United States
Tyler Winick's Contact Details
Tyler Winick work email
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Tyler Winick personal email
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About Tyler Winick
Tyler Winick is a Director of Chemistry Development at Synthego Corporation at Synthego Corporation. He possess expertise in data analysis, research, matlab, chemistry, microsoft office and 4 more skills.
Tyler Winick's Current Company Details
Synthego Corporation
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Director of Chemistry Development at Synthego Corporation
menlo park, california, united states
- Website:
- synthego.com
- Employees:
- 236
Tyler Winick Work Experience Details
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Director Of Chemistry DevelopmentSynthego Corporation Jun 2024 - PresentMenlo Park, California, United StatesLeader of the Chemistry Development team within the Technology organization, overseeing the establishment of an industry-leading oligonucleotide manufacturing workflow. The team strives to advance the field with a blend of preparative, analytical, and automation techniques. Robust technology transfer through change control and validation protocols illustrate the high standard for the development team as improvements are brought into the manufacturing lines.Leads planning for the Development team and helps shape the organizational goals for the company through product roadmpas and multi-year development cycles. Represents the company in diligence, audits, and client calls to explain and educate others in RNA manufacturing.Recent successes for the team include introducing a new product to the discovery line, a doubling of yield within the same starting batch size for the clincial line, and the introduction of new automation steps to streamline, reduce turn around time, and improve the quality of both the discovery and clinical lines.
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Associate Director, Process ChemistrySynthego Corporation Apr 2023 - Jun 2024Menlo Park, California, United StatesHead of the Process Chemistry Department within the Development organization, managing a team of scientist and engineering innovators in oligonucleotide manufacturing. Bringing in new chemical techniques and expanding the capabilities of the manufacturing platform are regular achievements for the team. Leading and completing root cause investigations in order to close CAPAs and prevent non-conformances are part of the teams core responsibilities.Represents the company as an RNA production subject matter expert internally and externally. Leads critical-path efforts to achieve organization-wide milestones and contributes to the planning of development goals.Highlights include opening a new manufacturing facility with a quadrupling of process lines, a doubling in purification throughput, stronger synthesis efficiency, overseeing the integration of multiple teams under one unified team, and a year of stable performance through careful management and development aid in the high-throughput discovery line.
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Manager, Process ChemistrySynthego Corporation Apr 2021 - Apr 2023Menlo Park, California, United StatesManaging a team of chemists and engineers, developing and scaling a micromole to millimole RUO and GMP RNA production line, from synthesis through purification. Expanding factory capabilities via New Product Introduction to meet market demand. Troubleshooting, running Root Cause Investigations, and monitoring three production lines are consistent responsibilities. Managing technology transfer for Large Scale and GMP production lines. Serves as a subject matter expert for RNA production, and provides triage and technical support across several teams. While Process Chemistry resides in the Manufacturing, Science, and Technology (MSAT) department, projects involve coordinating resources between MSAT, Operations, Development, Research, Quality, and Product teams to complete scaling and product expansion efforts.Projects completed includes adding and qualifying a parallel production line, quadrupling the throughput of deprotection and purification, creating a new assay for synthesis analysis to reduce rework time by 60%, and installing and qualifying larger instruments for a full platform overhaul that will quadruple the production batch size in Q1 2022. Upcoming work includes a second quadrupling of the batch size and preparing for additional parallel processing lines in a new facility within the next year.
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Development EngineerSynthego Corporation Jul 2019 - Apr 2021Menlo Park, CaliforniaUniquely positioned in an interdisciplinary role between development and operations, serving as a subject matter expert in oligonucleotide production while optimizing the RNA production facility. Designs and implements projects to increase product quality and throughput while reducing processing cycle times. Monitors, troubleshoots, and diagnoses problems in the factory, solves critical issues, and identifies and mitigates risk. Trains research associates and manufacturing supervisors on how to identify failure modes in oligonucleotide synthesis and the associated downstream processing. These efforts have resulted in a 45% increase in first-pass yield, a 100% increase in oligo molar yield, a 40% reduction in processing time, and a 35% increase in oligo production capacity.
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Chemistry Development ManagerSynthomics, Inc Dec 2018 - Mar 2019Managed oligonucleotide synthesis development operations. Managed and conducted chemistry optimization in the product life-cycle from proof of concept to beta demonstration. Researched, implemented, and scaled novel chemistry from proof of concept into manufacturing processes. Created Design of Experiments and participated in product design. Implemented project management practices to identify and execute key projects to meet production milestones. -
Assistant Engineering ManagerCentrillion Biosciences, Inc. Apr 2018 - Nov 2018Palo Alto, CaliforniaManaged domestic and international manufacturing operations to meet production goals across three facilities. Designed and conducted experiments for manufacturing research and participated in project design and strategy reviews. Created documentation for all manufacturing and testing processes, maintained document control, and trained all operators for each process. Managed the data analysis pipeline. -
Process Development EngineerCentrillion Biosciences, Inc. Jul 2015 - Apr 2018Palo Alto, CaliforniaCreated an optimized production workflow for oligonucleotide synthesis. This included adding new machinery to the production line, machinery and reagent qualifications, calibrations, and designing experiments to test the developing products. Conducted experimental research in the US facility and transferred knowledge to implement manufacturing procedures in two overseas facilities. Helped to manage the workflow of domestic manufacturing including scheduling shifts. Created a data analysis pipeline both with physical procedures and software tools. Created documentation and trained operators for manufacturing procedures. Programmed tools with LabView. Worked with numerous vendors and procured large pieces of equipment for manufacturing operations.
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Chemical Engineering StudentStanford University Sep 2011 - Jun 2015 -
Research Assistant And Intern ManagerSylvatex (Svx) Jul 2014 - Sep 2014Sunnyvale, CaliforniaLed the research being conducted to create and test diesel and biodiesel additives. This included troubleshooting formulation reactivity, creating improved biodiesel blends, and setting up testing protocols to meet ASTM standards. Managed the other interns and supervised laboratory work. Created reports and slide decks for business presentations. Other tasks included writing SOPs, ordering chemicals and laboratory supplies, and completing a beta testing cycle for scaled up production. -
Laboratory TechinicanNorthstar Biofuels Jul 2013 - Sep 2013Watsonville, CaliforniaPerformed numerous laboratory tests necessary to analyze and improve the production of biofuel. This included pH testing, centrifuge, gas chromatography, cloud points, titration, component analysis, and plant operations. Also created several laboratory and safety manuals, and became the lead trainer to teach operators to safely perform lab procedures.
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Research AssistantNaval Postgraduate School Jun 2009 - Sep 2012Monterey, CaliforniaCreated Economic Models and Monte Carlo simulations for new and future programs at Naval Postgraduate School. Completed accounting tasks for fiscal year end. Conducted research on Afghan insurgents for a fellowship program.
Tyler Winick Skills
Data Analysis
Research
Matlab
Chemistry
Microsoft Office
Statistics
Chemical Engineering
Laboratory
Organic Chemistry
Tyler Winick Education Details
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Chemical Engineering
Frequently Asked Questions about Tyler Winick
What company does Tyler Winick work for?
Tyler Winick works for Synthego Corporation
What is Tyler Winick's role at the current company?
Tyler Winick's current role is Director of Chemistry Development at Synthego Corporation.
What is Tyler Winick's email address?
Tyler Winick's email address is ww****@****bio.com
What schools did Tyler Winick attend?
Tyler Winick attended Stanford University.
What skills is Tyler Winick known for?
Tyler Winick has skills like Data Analysis, Research, Matlab, Chemistry, Microsoft Office, Statistics, Chemical Engineering, Laboratory, Organic Chemistry.
Who are Tyler Winick's colleagues?
Tyler Winick's colleagues are Artemisa Flores Torres, Claudio Sagal, Aleyda Mora Lopez, Nancy Dieu, Brian Chase, Neelima Vudathala, Jingren Yan, Cpa.
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