EyeGene, Inc. : Accomplishments of R&D / Business Development / IPO(Sep. 2000 – Mar. 2016) www.eyegene.co.kr• IPO in KOSDAQ Listed (2015.11)• IPO in KONEX Listed (2013.11)• Development of Therapeutics of Diabetic Retinopathy (“EG-Mirotin”): pre-clinical in Korea & EU, Clinical Phase I in Netheland, NOW Clinical Phase IIa in France• Development of Therapeutics of Chronic Ulcer, Bedsore (“EG-Decorin”): pre-clinical in Korea, NOW Clinical Phase I & II in Korea w/ HUONS• Development of Human Papilloma Vaccine (“EG-HPV”): pre-clinical in Korea & EU, Clinical Phase I in Korea, NOW Clinical Phase II preparation in Korea • Development of Novel Vaccine Adjuvant (“EGvac”) • Development of Therapeutics of fibrosis (Scarless wound healing for eye : “EGS001”): Identification using proteomics of human amniotic membrane NOW Clinical Phase I&II preparation in Korea• Development of Diagnostics of Diabetes Complication (such as Diabetic Retinopathy): Bio-marker Identification using proteomics : from human eye• Development of Immunotherapeutics of cancer (“Zycan”) : pre-clinical stage, pilot production, Animal test (Efficacy:Animal model) (bladder cancer, melanoma, colon cancer & prostate cancer)- Technological Transfer to Pharmaceutical company (Domestic)1. Human papiloma vaccine : ChongKunDang Pharm (CKD pharm) (2009)- Co-development of vaccine / technology Licencing-out(Korea/China)- “super biosimilar”2. Therapeutic for Chronic Ulcer : “HUONS” (2009)- Co-development of BIO new drug / technology Licencing-out(Korea)3. Immunotherapeutics of cancer : Daewoong Pharmaceuticals (2002)- Co-development of new drug (pending)4. Diagnostics of Diabetic Retinopathy : Kuhnil Pharmaceuticals (2004)- Licence-out (pending)

CJ Corp.: Accomplishments of Research & Development(Feb. 1988 – Aug. 2000)• Development of Teicoplanin : project leader 1999-2000: API, Fermentation & Purification, scale-up• Development &Screening of novel anti-inflammatory from microbes 1998-1999: New-drug development (basic research) • Development of high-yield microbes : project leader 1996-1997: Fermentation & Purification, scale-up• Development of Streptokinase for inj. : project leader 1994-1995: Purification of protein, scale-up (pilot)• Development of Vancomycin (glycopeptide antibiotic) 1990-1993: Project leader for Purification, scale-up, commercialization• Development of HBV (from animal cell culture) : researcher 1989-1990: Cell culture & Purification, scale-up• Development of Diagnostics : researcher 1988-1989: Diagnostic of pregnancy, cancer……AWARDS• Awards of CJ group Technology (Bronze), 1994: Development of Vancomycin antibiotics• Awards of CJ group Technology (Bronze), 1997: Development of high-yield microbes for fermentation