A lead instructor for undergraduate biomaterials lab courses, a guest instructor in a Nanomedicine graduate course. Co-mentor in three NIH pre- and postdoctoral training programs, including Interdisciplinary Biomedical Imaging (T32EB007509), Cancer Biology (T32CA059366) and Cancer Pharmacology (R25CA148052). Supervised a large number of students and early-stage scientists (mentored 11 graduate students, 1 medical student, 5 postdoctoral fellows, and more than 85 undergraduate research assistants).

Provide technical leadership for interdisciplinary R&D teams in method development, product validation, therapeutics, imaging agents, immunotherapy, immunohistochemistry, stem and cancer cell biology, medical devices, radionuclides, and preclinical imaging and testing groups. Develop, improve, and implement analytical methods. Participate in R&D technical and strategic planning. Recruit and mentor R&D personnel. • Member of the senior leadership team. Responsible for management of a diverse laboratory of ~ 50 researchers and administrative staff and a budget of ~ $ 5 MM.• Actively participated in product development, synthesis, characterization, and performance validation of complex materials with self-driven and collaborated projects. • Explored the outcome of predicting tumor signal by image processing with PET, CT, SPECT, and MRI modalities.• Developed 18F and Tc-99m radiotracers for cancer imaging and validated signal enhancement for PET/CT/SPECT imaging. • Performed purity validation and trace analysis testing for therapeutics and contrast agents by detecting organic/elemental composition and evaluating impurities using HPLC, Electrochemical, LC, GC/MS, UV-Vis, FTIR, AA, ICP-OES, and ICP-AES. • Directed the development of cancer prognostic products and devices. Collaborated with MRI physicists, engineers, and the imaging core, a prototype instrument has developed with radio frequency (RF) triggered function to diagnose and treat cancer.• Responsible for editorial, scientific, and policy review of project proposals, manuscripts, and presentations. • Collaborated, consulted, and engaged with Industries, universities, and hospitals for potential new technologies, method/product development, and application. • Analyzed, resolved, and presented complex characterization, imaging data by utilizing statistical and graphical tools. • Gathered critical technological knowledge by attending, presenting and brainstorming in global conferences and workshops.

• Mentored, trained, developed, and evaluated direct reports and projects of group members and lab personnel, and ensure adherence to safety, housekeeping, and quality standards.• Maintained laboratory equipment performance implementing SOPs, establishing quality standards, troubleshooting procedures, certifying instrument performance, arranging equipment replacement, service, and repair.• Maintained laboratory supplies inventory and proven cost reduction (cut the cost by 40 % on supplies). • Managed more than $5 MM budgets including federal grants and foundation awards. • Maintained, implemented, and enforced laboratory Chemical Hygiene plan according to OHSA and EHS standards. 9 years of experience, working as a research laboratory safety officer with 100% safe operational practice.• Prepared, filed, and applied annual/quarterly evaluation report and communications based upon OSHA and EPA new regulations and/or revisions to existing regulations.• Enforced environmental, health, and safety guidelines to evaluate equipment, physical facilities, operation techniques, procedures, chemicals, tissue, veterinary, and human subjects.

Be fully responsible for routine laboratory tasks such as operating and maintenance of lab equipment, as well as developing new techniques under limited supervision, coordinating lab activities, performing complex analytical procedures, designing, evaluating, and optimizing experimental techniques. Mentor, and train research assistants and laboratory personnel. Carried out a research program to optimize and validate methods using chromatography, immunohistochemistry, imaging, and Spectroscopy for polymers, lipids, nanoparticles, crosslinkers, drug formulations, imaging agents, and peptides. Coordinated purity and validation of ingredients in nanoparticle formulations using HPLC, FTIR, AA, ICP-OES, and ICP-AES. Developed clinically relevant anatomical and molecular imaging agents for MRI, CT, radionuclide (SPET, PET), and optical imaging to enable non-invasive interrogation of disease and highly precise diagnosis and prognosis of lethal cancers. Co-invented formulation for therapeutics by assembling hard, soft, and polymer nanomaterials capable of releasing trap materials with radio frequency (RF) triggered function. Develop experimental designs including the design of experiments, carrying out all pertinent laboratory and analysis techniques, sample preparationSupervise and interact with postdoctoral scholars, graduate students and other lab personnel to maintain budgets for a variety of laboratory projects including federal grants and foundation awards.Contribute preliminary data, background and significance and experimental design for grant proposals

Lead and manage the development of new products platforms and perform synthesis, characterization, and performance validation of polymeric, organic, and inorganic constituents for self-driven and collaborated projects. Manage and implement immunohistochemical core.• Co-developed the nanochain technology for image-guided and modulated delivery of drugs (U.S. Patent 9439966, WIPO Patent, 2013056092). Due to enhanced site-specific vascular targeting and radiofrequency-triggered drug release, this platform facilitates effective delivery of drugs into hard-to-reach cancers, which has the potential to unfold the field and allow significant expansion of therapiesto the disease where success is currently very limited. Engineered cost-effective scale-up platform for potential commercialization.• Conducted formulation stability validation and testing (lyophilization, drug loading, particle size, composition, shelf-life). • Implemented, executed and managed immunohistochemical research with various antibody combinations used as a diagnostic and therapeutic predictor for cancer.• Worked on various cell based-bioassays including WST-1, ELISA, CCK-8, and Comet, etc. and applied to animal studies for cancer pretreatment.• Contributed to the collaboration project of development of therapeutic and imaging agents using viral nanotechnology that interface between virology, biotechnology, chemistry, and materials science.