Samuel Wyss Email & Phone Number

West Lafayette, Indiana, United States

▪ Accelerated electroporation simulation suite with various HPC techniques and libraries resulting in a speedup of >100x allowing for multi-timescale events to be modeled in a time efficient manner▪ Integrated a custom time-domain heat-equation solver using the Crank-Nicholson implicit method into electroporation model enabling modeling of multi-physical phenomenon▪ Mentored 5+ undergraduate students through computational physics projects facilitating hands-on learning of multidisciplinary topics not generally taught in classes▪ Designed scalable particle swarm optimization framework for modeling millisecond scale nonlinear Hodgkin-Huxley neuron dynamics stimulated by nanosecond pulse trains, allowing for development of novel waveforms for neuronal stimulation

West Lafayette, Indiana, United States

▪ Facilitated transformation of previously incorrect numerical model into a complete computational suite with a small team of undergraduate developers and faculty advisors▪ Refactored monolithic electroporation model through test-driven development into modular OpenPore platform built on established software design patterns allowing for enhanced maintainability, and expandability▪ Investigated cellular fractional pore area following electric pulse delivery to develop electroporation scaling laws for different pulse parameters▪ Implemented chemical species transport into electroporation model using a finite difference Nernst-Planck regime to model the complex behavior of ions during cellular exposure to electric pulses

West Lafayette, Indiana, United States

▪ Optimized electroporation model by implementing proper data structures leading to an execution timereduction of approximately 650%▪ Characterized effects of waveforms delivered by impedance mismatched pulse forming networks on cellular electroporation efficiency▪ Disseminated research findings at both IEEE IPMHVC and the Purdue Engineering Undergraduate Research Office SURF Symposium covering audiences with a wide array of technical backgrounds and experiences

West Lafayette, Indiana, United States

▪ Eliminated severe memory leaks in electroporation model resulting in a constant memory footprint enabling previously impossible simulations to be performed on low cost machines▪ Adapted the finite difference method to simulate plasma membrane pore dynamics induced by electric fields using MATLAB to model the complex interactions between mammalian cells and electric pulses▪ Refined simulation meshing methods to prevent spherical coordinate singularities while maintaining complex cellular geometries

United States

▪ Managed and developed webpage for 2024 IEEE International Power Modulator and High Voltage Conference coordinating information between scientists, engineers, and vendors for successful operation of conference.Homepage: http://www.ipmhvc.com/2024-home/

Van Wert, Ohio, United States

▪ Created scheduling system via Microsoft Excel to aid in decision-making allowing for a more effective use of machine shop resources▪ Validated control systems to ensure proper communication between devices upon initial power up▪ Planned and implemented CNC tooling organization system for efficient tool changing and long-term storage▪ Machined >500 parts for automation products using a variety of fabrication techniques ranging from hand tools to CNC milling

West Lafayette, Indiana, United States

▪ Simulated 3D nondestructive electrical eddy current testing for aerospace structural analysis via Ansys Maxwell▪ Harnessed the finite element method to identify and characterize variable defect diameters in metals▪ Researched various meshing techniques to reduce computation time and provide more accurate results for complex geometries

Master Of Science - Ms, Nuclear Engineering

Activities and Societies: Specialization in Computational Science and Engineering through Purdue CIGP program

Bachelor Of Science - Bs, Nuclear Engineering

Academic Honors Diploma | Summa Cum Laude

Activities and Societies: Technology Student Association (President), National Honor Society, Bellmont Early College, STEM Tutoring.