Y. Albert Pan Email and Phone Number
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• Ph.D. scientist with background in neurobiology, developmental biology, and genetics• Developed animal models (mouse and zebrafish) and in vitro assays using primary hippocampal culture and cell line (tau phosphorylation assay)• Expert in confocal imaging and neural circuit (axon) tracing• First developed Brainbow multi-fluorescent labeling in zebrafish to enable tracing of specific neural circuits and cell lineagesPublications:Pan, Y. A., Caron, S. J., and Schier, A. F. (2012). BAPTI and BAPTISM birthdating of neurons in zebrafish.. Cold Spring Harb Protoc. 2012 Jan 1;2012(1). pii: pdb.prot067520.Pan, Y.A., Choy, M., Prober, D. A., and Schier, A. F. (2012). Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development 139, 591-600.Pan, Y. A., Livet, J., Sanes, J. R., Lichtman, J. W. and Schier, A. F. (2011). Multicolor Brainbow imaging in zebrafish. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5546.Barnes, A. P., Lilley, B. N., Pan, Y. A., Plummer, L. J., Powell, A. W., Raines, A. N., Sanes, J. R. and Polleux, F. (2007). LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129, 549-63.Kishi, M.*, Pan, Y. A.*, Crump, J. G. and Sanes, J. R. (2005). Mammalian SAD kinases are required for neuronal polarization. Science 307, 929-32. (*co-first authors) Pan, Y. A. and Sanes, J. R. (2004). Non-invasive visualization of epidermal responses to injury using a fluorescent transgenic reporter. J Invest Dermatol 123, 888-91.Pan, Y. A., Misgeld, T., Lichtman, J. W. and Sanes, J. R. (2003). Effects of neurotoxic and neuroprotective agents on peripheral nerve regeneration assayed by time-lapse imaging in vivo. J Neurosci 23, 11479-88. (cover article)
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Associate ProfessorFralin Biomedical Research Institute At VtcRoanoke, Va, Us -
Associate ProfessorFralin Biomedical Research Institute At Vtc Jul 2017 - PresentRoanoke, Virginia, Us -
Assistant ProfessorMedical College Of Georgia At Augusta University Jul 2013 - Jul 2017Augusta, Ga, UsNeural circuits are information highways that connect diverse neuronal types and allow them to perform complex functions. The goal of my research is to uncover the molecular and cellular mechanisms that regulate neural circuit formation, which are important for neurological disorders such as Down syndrome and autism. Zebrafish is a uniquely advantageous system for this endeavor. It is transparent, which allows continuous visualization of circuit development at high resolution. The small number of cells and compact size also make it a more tractable system to investigate how complex brain structures emerge in a vertebrate organism (Pan et al. Development 2012). I am also developing tools that would allow detailed mapping of neural circuits, e.g. Brainbow multi-color imaging (Pan et al. Development 2013) and viral trans-synaptic tracing. -
Research AssociateHarvard University Jan 2006 - Jun 2013Cambridge, Massachusetts, UsDr. Alex Schier lab, Dept of Molecular and Cellular Biology-Develop a novel zebrafish system to investigate axonal wiring of somatosensory and pain neural circuits-Identify Robo2 (axon guidance receptor) as an essential factor in determining specificity of neural circuitry-Apply multi-color (Brainbow) labeling technique for in vivo neuronal labeling and tracing in zebrafish-Collaborate with Dr. C. Cepko at HMS to apply viral trans-synaptic neural circuit tracing technique to zebrafish-Mentored one undergraduate and three graduate students -
Graduate StudentWashington University School Of Medicine Sep 2000 - May 2005St. Louis, Mo, UsDr. Joshua Sanes lab, Dept of Anatomy and Neurobiology-Identified the role two novel kinases, SAD-A and SAD-B, in neuronal polarization and cortical neuron migration.-Generated conditional mouse knockout for SAD-A to investigate its role in postnatal synaptogenesis.-Collaborated with Jeff Lichtman lab to develop novel live imaging assays for nerve regeneration after injury-Collaborated with Franck Polleux lab to discover a novel function of the tumor suppressor gene, LKB1, in neuronal polarization
Y. Albert Pan Skills
Y. Albert Pan Education Details
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Washington University School Of Medicine In St. LouisDevelopmental Biology -
National Taiwan UniversityZoology
Frequently Asked Questions about Y. Albert Pan
What company does Y. Albert Pan work for?
Y. Albert Pan works for Fralin Biomedical Research Institute At Vtc
What is Y. Albert Pan's role at the current company?
Y. Albert Pan's current role is Associate Professor.
What is Y. Albert Pan's email address?
Y. Albert Pan's email address is ya****@****ard.edu
What schools did Y. Albert Pan attend?
Y. Albert Pan attended Washington University School Of Medicine In St. Louis, National Taiwan University.
What skills is Y. Albert Pan known for?
Y. Albert Pan has skills like Developmental Biology, Molecular Biology, Neuroscience, Cell Biology, Confocal Microscopy, In Vitro, Genetics, In Vivo, Animal Models, Assay Development, Science, Cell.
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