Scipio bioscience has developed the Asteria benchtop kit to perform sample preparation for single-cell RNA sequencing (scRNA-seq) based on a reversible hydrogel technology called “RevGel-seq”. To analyze the raw sequencing data derived from the Asteria kit, the a cloud-based solution Cytonaut has been developed as a companion software empowering all biologists to perform data pre-processing, post-processing and interactive data visualization in full autonomy..• Major development of the bioinformatics part of the Cytonaut solution by:Converting the workflow of the whole pre-processing pipeline from Snakemake to Nextflow, and developing the whole post- processing pipeline with Scanpy, running on Amazon Web Services (AWS)Management of the interface between Bioinformatics team and Software Development team• Analysis of scRNA-seq data for the Wet-Lab R&D team, from sequencer files (BCL) to differential gene expression and cell type annotation• Implementation of CI/CD with GitLab, based on unit tests and user tests with specific error handling• Creation of dockers to work with AWS ECS

The LHUB is a multi-site clinical biology laboratory based on 5 Brussels hospitals. Its mission is to analyze all data coming from these hospitals covering 7 different sectors, including chemistry, immunology and cytology.• Setting of the 2 different General Laboratory Information Management Systems (LIMS)• Alignment of these 2 LIMS entities by merging and ensuring continuous improvement• Implementation of a reporting solution

The Laboratory for the Research of Neurodegenerative Diseases works on Alzheimer and Parkinson diseases.• Analysis of scRNA-seq data for every project in the laboratory, from sequencer files (BCL) to differential geneexpression.• SNPs-Gene association study with p-value analysis based on several statistical tools (ex: Magma).• Creation of dockers (Singularity) to work in collaboration with external laboratory (Imperial college London).

Genomic Vision is a biotechnology company that develops and commercializes diagnostic tests and pharmacology DNA research tools based on molecular combing.• Barcode design approach for study of genetic structural variations and/or replication origin localization• Comparative study of different alignment tools to determine the best adapted for studies related to molecular combing• Optimization and automation of the use of bioinformatics tools

Professor Gilad’s laboratory focuses on the study of the genetic architecture and gene regulation in human population and primates.• Study of differences in the phosphorylation of protein network within the Yoruba population and between primates.• Use of bioinformatics comparison tools for the annotation of inter-individual and inter-species genetic variation and prediction of the effects they may cause in the known genes• Selection of genetics variations (SNPs) related to protein phosphorylation networks

Technology and Innovation• Development of biology probes constituting the genetic barcode• Characterization of biological parameters related to molecular combing• Using bioinformatics tools to facilitate the analysis of resultsIndustrialization and quality control• Manage and control glass slide coting protocol• Collaborate and train specialized companies on glass slide coting• Improve and Implement quality control protocol

GenHotel is a genomic research laboratory dedicated to rheumatoid polyarthritisdisease: study genomic factors candidate.• Search candidate genes thanks to bioinformatics tools• Study SNP of candidate genes using Polymerase Chain Reaction techniques todiscover their impact on the disease.