Yanni Lin Email & Phone Number
@gatech.edu
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Who is Yanni Lin? Overview
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Yanni Lin is listed as Chief Scientist at Cure Genetics Co., Ltd at 克睿基因 Cure Genetics, based in San Diego, California, United States. AeroLeads shows a work email signal at gatech.edu and a matched LinkedIn profile for Yanni Lin.
Yanni Lin previously worked as Co-founder and Chief Scientist at 克睿基因 Cure Genetics and Co-founder and Chief Technology Officer at 克睿基因 Cure Genetics. Yanni Lin holds Ph.D., Biomedical Engineering from Georgia Institute Of Technology.
Email format at 克睿基因 Cure Genetics
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About Yanni Lin
10+ years of experiences in genetic engineering in mammalian cells / cell engineering using TAL effector nucleases (TALENs) and CRISPR/Cas9 systems.
Listed skills include Molecular Biology, Cell Culture, Fluorescence Microscopy, Pcr, and 20 others.
Yanni Lin's current company
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Yanni Lin work experience
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Co-Founder And Chief Technology Officer
R&D leader responsible for scientific and technological development of cell therapies.http://www.curegenetics.com/
Scientist
Mammalian Synthetic Biology, Immunology Group• Generated cell lines to facilitate in vitro functional assays to assess immune responses.• Generated large deletion and gene knock-in in human and pig cells using CRISPR/Cas9.• Implemented methods to improve CRISPR/Cas9 multiplexing.• Analysis of CRISPR off-target effect.
Phd
Optimizing activities and investigating in the off-target effect of engineered nucleases, which are being used for correcting mutated sequences in genetic diseases (e.g. Sickle Cell Disease) or disruption of genes (e.g. viral genes such as HIV).__________________________________________________________________________________• Working closely with 24 researchers from 7 universities in a multidisciplinary center for translational Sickle Cell Disease treatment. Communicating data in monthly video conferences and semi-annual review meetings.• Edited successful application for $50,000 Seed Grant (HIV) from Children’s Healthcare of Atlanta & Emory.• Developed/optimized 8+ critical experiment protocols widely used in the lab, including optimizing the automation of high-throughput DNA purification, transfection conditions of 293T cells, and genomic mutation detection assay.• Built a high-throughput pipeline for TALEN/CRISPR assembly and testing in collaboration with colleagues.• Modeled the activity of TALE Nucleases for gene modification using 205 nucleases as the training set. Increased activity by >3 folds.• Identified new safety concerns on CRISPR nuclease by exploring 100+ potential off-target sites using next-generation sequencing tools.• Functionalized nano-particles with polymers attached to functional groups.
Master Degree
• Optimized an anaerobic protein expression system for mutants of E. coli Cyt bd oxidase, part of the energy chain. • Cloned and expressed a novel Cyt bd Oxidase from Chlorobium ferrooxidans.• Identified a key residue in proton conducting channel of Cytochrome bd Oxidase from E. coli based on FTIR, UV-Vis spectrometry, pyridine hemochromogen assay and oxidase activity assay.
Undergraduate Research Assistant
• Optimized protein crystalization conditions. Obtained crystals diffracted to 8Å for Pyrroline-5-carboxylate Reductase from a microbial (Sulfolobus solfataricus P2). Characterized the polymerization of this protein based on chemical cross-linking and dynamic light scattering.
Yanni Lin education
Ph.D., Biomedical Engineering
M.S., Biochemistry
B.S., Biological Science And Biotechnology
Education record
Frequently asked questions about Yanni Lin
Quick answers generated from the profile data available on this page.
What company does Yanni Lin work for?
Yanni Lin works for 克睿基因 Cure Genetics.
What is Yanni Lin's role at 克睿基因 Cure Genetics?
Yanni Lin is listed as Chief Scientist at Cure Genetics Co., Ltd at 克睿基因 Cure Genetics.
What is Yanni Lin's email address?
AeroLeads has found 1 work email signal at @gatech.edu for Yanni Lin at 克睿基因 Cure Genetics.
Where is Yanni Lin based?
Yanni Lin is based in San Diego, California, United States while working with 克睿基因 Cure Genetics.
What companies has Yanni Lin worked for?
Yanni Lin has worked for 克睿基因 Cure Genetics, Synthetic Genomics, Georgia Institute Of Technology, University Of Illinois At Urbana-Champaign, and Tsinghua University.
How can I contact Yanni Lin?
You can use AeroLeads to view verified contact signals for Yanni Lin at 克睿基因 Cure Genetics, including work email, phone, and LinkedIn data when available.
What schools did Yanni Lin attend?
Yanni Lin holds Ph.D., Biomedical Engineering from Georgia Institute Of Technology.
What skills is Yanni Lin known for?
Yanni Lin is listed with skills including Molecular Biology, Cell Culture, Fluorescence Microscopy, Pcr, Western Blotting, Protein Expression, Transfection, and Biochemistry.
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