Yi-Ju Chen Email & Phone Number

Greater San Diego Area

Greater San Diego Area

• Identified the underlying physical mechanism and developed a quantitative theory for bacteriophage genome delivery into live bacterial cells. Addressed long-standing conceptual problems associated with the viral.
• Constructed biophysics-based models to: Describe the signal transduction and adaptation in the fly olfactory receptor neurons & Explain the statistical properties of the receptor repertoire, which are key to the coding.
• Authored manuscripts for publication.

Greater San Diego Area

• Analyzed fly olfactory response measurements to predict odor mixture processing from responses to pure odorants.
• Developed and applied biophysical theory to reveal latent variables in the current experimental design. Resulted in significant improvements to the experimental design & Facilitated proper interpretation of the results.

Greater Los Angeles Area

• Conceived and designed the study of the molecular balance, dynamics, and cell-to-cell variability in the viral lytic production process, using single-molecule DNA fluorescence in situ hybridization and fluorescently.
• Optimized the real-time, single-virus visualization the bacteriophage genome ejection process and examined its speed and driving forces.
• Adopted the tethered particle motion method to investigate sequence-dependent flexibility of DNA and how it modulates the kinetics of protein-mediated structural rearrangement of DNA, which is prominent for.
• Wrote papers and sections of NSF/NIH grant proposals.

Greater Los Angeles Area

• Held weekly sessions, developed practice problems/experimental projects, and evaluated student comprehension for graduate-level courses in bioengineering/applied physics (physical and synthetic biology boot camp.
• Demonstrated microscopy/wet lab techniques and MATLAB image processing to biology undergrads (the great ideas of biology: an introduction through experimentation).

Ph.D., Physics

Activities and Societies: • Research group: Physical Biology of the Cell • Dissertation: The Mechanical Genome in Regulation and Infection

B.S., Physics

B.S.E., Electrical Engineering