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R&D Scientist with 10+ years of hands-on experience in synthetic organic chemistry, catalysis, analytical chemistry and drug discovery. Extensive experience in modern organic synthesis, asymmetric catalysis, medicinal chemistry, chromatographic technologies, and structural characterization.Specialties: Synthetic Organic Chemistry; Multi-Step Synthesis; Total Synthesis; Organocatalysis; Asymmetric Synthesis; Structure Based Drug Design; Natural Product Organic Chemistry; Materials Chemistry; and molecular spectroscopy.
Biotech Startup
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ScientistBiotech Startup 2011 - Present• Designed and synthesized complex molecules and used as tools in biological or biochemical assays, imaging and studies.• Developed new methodologies and manufactured dyes and other bioanalytical reagents for bioconjugation.• Performed custom synthesis of photometric probes and custom development of assays.
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ScientistSupergen, Inc. (Now Astex Pharmaceuticals) 2008 - 2011• Designed and optimized synthetic routes for the discovery and development of new therapeutic agents.• Worked in drug discovery with extensive experiences in SAR studies for better potency, selectivity, and drug-like profiles of lead compounds.• Preformed as a lead in a team of chemists and biologists which advanced two projects to preclinical evaluation.
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Postdoc Research AssociateIowa State University 2003 - 2008Ames, Iowa, Us• Discovered new synthetic route and developed antidiabetic procyanidin analogs for preclinical testing. • Performed study towards the total synthesis of antibacterial kinamycins and other complex compounds. -
Postdoc Research AssociateColorado State University 2002 - 2003Fort Collins, Co, Us• Developed asymmetric synthetic methods for the preparation of 3-membered ring compounds from unfunctionalized olefins. -
Postdoc Research AssociateInstitute Of Fine Organic Chemistry Research, France 2001 - 2002• Explored the most reactive organolithium complexes for asymmetric synthesis.• Investigated the structures of chiral lithium amide complexes and reaction mechanism using NMR techniques.
Yi Yuan Skills
Yi Yuan Education Details
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Sichuan UniversityOrganic Chemistry
Frequently Asked Questions about Yi Yuan
What company does Yi Yuan work for?
Yi Yuan works for Biotech Startup
What is Yi Yuan's role at the current company?
Yi Yuan's current role is R&D Chemist.
What is Yi Yuan's email address?
Yi Yuan's email address is oo****@****hoo.com
What schools did Yi Yuan attend?
Yi Yuan attended Sichuan University.
What skills is Yi Yuan known for?
Yi Yuan has skills like Medicinal Chemistry, Organic Synthesis, Drug Discovery, Heterocyclic Chemistry, Bioconjugate Chemistry, Dye Chemistry, Peptide Chemistry, Asymmetric Catalysis, Lc Ms, Hplc, Nmr, Analytical Chemistry.
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