3D structures. Protein expression with baculovirus expression system, and protein purification by HPLC/FPLC.

Thesis title: Metabolic Heterogeneity In Breast CancerIdentified novel roles of TP53 induced glycolysis and apoptosis protein in both stroma and epithelial cancer cells, published in Nov 2016.Demonstrated the anti-estrogen resistance in breast cancer that is induced by the tumor environment and can be overcome by inhibiting mitochondrial function, published in Nov 2011.Identified the oxidative stress and stromal caveolin-1 related intracellular signal pathways, including cell metabolism, oxidative phosphorylation and cell apoptosis, in the tumor microenvironment.Mentored and trained medical and pre-med college student in lab techniques including cell culture, protein expression assays, flow cytometry and multicolor confocal microscopy.

Generated Brain Natrieretic peptite point mutation mouse model for the hypertension study and performed corin protein expression assays.Genotyped and collected blood sample from mice.

Investigated candidate genes in drug design to overcome the cellular damage caused by radiation in prostate cancer model through mice tissue samples by real-time PCR.Analyzed microarray data and interpreted cell progress and biological signal pathways in radiated mice model.