Yuzhen Ke Email & Phone Number

St Louis, Missouri, United States

• Provided statistical support for clinical study design such as sample size power calculation and generation of randomization schedule for clinical trials
• Provided statistical review of clinical trial documents such as Protocol, Case Report Forms (CRFs), Data Management Plans (DMPs) and etc.
• Assisted senior Biostatisticians in writing and reviewing Statistical Analysis Plans (SAPs)
• Drafted SAS programming specifications (Table/Listings/Figure shells) for clinical data analyses
• Designed statistical guide for SAS programmers to conduct the clinical data analyses
• Performed independent programming validation for efficacy and safety results of clinical data analyses

West Lafayette, Indiana, United States

• Identified the cancer-recurrence associated oncogenes with data sets from The Cancer Genome Atlas and helped provide theoretical support in diagnosis and prevention of tumor recurrence
• Utilized Purdue Scholar (a computer cluster) to perform exploratory data analysis in R on 100K+ patients and 200K oncogenes includingPerformed preliminary analysis of data and preprocessed the data set by duplicates.
• Applied two-sample t-test and Cox proportional hazards regression to identify possible significant oncogenes that influence tumor recurrencePerformed the false discovery rate (FDR) to improve the accuracy of multiple.
• Visualized results by dimensionality reduction using Principal Component Analysis (PCA) to identify significant tumor-recurrence genomic bio-markers

West Lafayette, Indiana, United States

• Researched on misrepresentation of insurance risk during the underwriting process and analyzed its influence
• Developed a predictive Gamma model based on EM algorithm and run the simulation to test the feasibility and usefulness of the Gamma model

Master'S Degree, Mathematical Statistics And Probability

Bachelor Of Science - Bs, Applied Statistics

Bachelor Of Science - Bs, Actuarial Science