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Accomplished, hard-working scientist with over 10 years of experience in drug discovery and development. Notable accomplishments include developing novel assays that accelerated drug candidate identification and supported successful fundraising rounds. My expertise spans analytical development, in vitro pharmacology, and preclinical discovery. Known for driving results and fostering collaboration, I thrive on pushing scientific boundaries to advance drug discovery. Let's connect to explore innovative opportunities in biotech.
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ScientistResilienceBoston, Ma, Us -
ScientistOmega Therapeutics Sep 2020 - PresentCambridge, Massachusetts, UsKey driver of in vitro pharmacology efforts and ex vivo biochemical assay development, supporting tissue fibrosis and regenerative medicine programs.I spearheaded in vitro pharmacology efforts, including developing an assay in primary human hepatocytes to screen mRNA-based, LNP-encapsulated Epigenomic Controllers. This initiative significantly accelerated the drug discovery program, leading to the identification of a Development Candidate in an accelerated timeframe. -
Senior Research AssociateOmega Therapeutics Jun 2019 - Sep 2020Cambridge, Massachusetts, Us -
Research Associate IiTakeda Mar 2017 - Jun 2019Tokyo, JpTechnical lead for assay development in Vaccines Discovery for evaluation of anti-drug antibody response in vaccinated serum samples -
Research Associate, Analytical DevelopmentSeres Therapeutics Nov 2015 - Jan 2017Cambridge, Massachusetts, Us• Participating in developing Ecobiotic therapeutic products to treat metabolic, inflammatory andinfectious diseases• Working with senior staff, develop, qualify and validate assays for process monitoring and productrelease• Authoring assay SOPs and operating the assays to produce accurate, precise, trustworthy data• Qualify analytical instruments for use• Transfer assays and information to internal, academic, and commercial partners• Participate in developing core intellectual property• TCNP assay to determine Total Carbohydrate Nucleic Acid Protein concentrations of bioprocessintermediates• HPLC Analysis of Glycerol/Ethanol in drug product, placebo and intermediates• DNA and RNA quantification assays (Nanodrop) -
Research TechnicianDana-Farber Cancer Institute 2013 - 2015Boston, Ma, Us• Expertise in liquid handling platforms: Tecan Freedom EVO, Aquarius, Genesis workstation, Genetix Qpix in 96 and 384 well format• Robotic re-array (Cherry Picking) of DNA minipreps, liquid cultures and glycerol stocks• Pipeline for Yeast two-Hybrid (Y2H) screening and phenotyping potential protein interactions• Performed large scale PCR (yeast and bacterial)• Plasmid DNA isolation (Mini/Maxi Prep)• Bacterial and yeast transformations• Protein Complementation Array (PCA) and ELISA• Preparation of reagents, gels, and selective media and controls• Competent cell preparation• Center for Excellence in Genome Science (CEGS) Scholar participant in numerous Harvard Medical School and Genomic conferences -
Research AssistantBoston University 2011 - 2013• Identification of molecular origins of vibrational signals of bacteria using Raman Spectroscopy• SERS (Surface Enhanced Raman Scattering) approach for Rapid Urinary Tract Infection Diagnostics• Conducted basic and applied research on bacterial enrichment procedure from urine• Demonstration of SERS sensitivity for UTI causing bacteria at medically relevant concentrations, developed library of reference spectra for bacterial identification and determined effect of antibiotics on SERS procedure* Assisted in carrying out analysis of purine metabolism in human blood and bacteria* Collected and analyzed biological data
Yoseph Kassa Skills
Yoseph Kassa Education Details
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Northeastern UniversityBiochemistry
Frequently Asked Questions about Yoseph Kassa
What company does Yoseph Kassa work for?
Yoseph Kassa works for Resilience
What is Yoseph Kassa's role at the current company?
Yoseph Kassa's current role is Scientist.
What is Yoseph Kassa's email address?
Yoseph Kassa's email address is yk****@****ics.com
What schools did Yoseph Kassa attend?
Yoseph Kassa attended Northeastern University.
What skills is Yoseph Kassa known for?
Yoseph Kassa has skills like Cell Biology, Clinical Research, Genetics, Cell Culture, Pcr, Western Blotting, Molecular Biology, Data Analysis, Hospitals, Healthcare, Biochemistry, Life Sciences.
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