Young Lee, Ph.D. Email & Phone Number

Indianapolis, IN, US

[Development of a novel disease modifying oral therapy for pulmonary arterial hypertension]- Leading SBIR phase II by establishing objectives, timelines, budgets, and managing CROs studies. - Monitoring project risks by identifying potential issues early and developing contingency plans. - Coordinating the review and submission of research protocols.

Indianapolis, Indiana, United States

[Development of novel therapeutic in a preclinical model of kidney and lung disease progression]- Developed formulation for oral dose to determine the PK and PD profiles and in vivo efficacy. - Performed RNA-seq, qPCR, WB, ELISA analysis and validated mechanism of action.- Maintained equipment, drafted SOPs, documented experiments in adherence to.

Indianapolis, Indiana, United States

[A novel transcriptional modulator as a disease modifying therapy for cardiometabolic disease]- Designed reporter assay for screening and completed SAR and lead optimization with chemists. - Generated and structured preliminary data for grant applications, securing >$1 million in funding.[Engineering a protein to optimize activity and extend in vivo.

Indianapolis, Indiana, United States

[Develop a novel long-acting protein and assess its activity as a bio-therapeutic molecule]- Cloning, expression, purification, and PEGylation of human and pseudomonas protein.- Performed chromatographic separation of metabolite stereoisomer using HPLC to evaluate efficacy.[Intratracheal delivery of liposomal cerivastatin as an approach for the treatment.

Lafayette, Indiana, United States

[Drug formulation of lipid-based nanoparticles and targeted drug delivery to bladder tumor site]- Developed liposomal formulations encapsulating APIs, nucleic acids, and macromolecule complexes.- Fabricated liposomes with targeting peptide and evaluated intracellular trafficking and localization.

Doctor Of Philosophy (Ph.D.), Organic Chemistry

Bachelor'S Degree, Chemistry