Yu-Chen (Janet) Pan Email & Phone Number

• Collaborated and developed a pipeline for extracting somatic and germline variants from high throughput single cell data (sciATAC-seq) in Drosophila melanogaster and human fetal embryos (HPCC, Linux, Snakemake, R)• Designed the application of quality control analyses from the extracted variants • Conducted mutational signature analysis, comparing results with the Catalogue of Somatic Mutations in Cancer (COSMIC) to explore mutagenesis mechanisms and rates across tissues during development (R, Python)

• Led PrecisionTox project: - Performed extreme QTL mapping (xQTL) experiments to explore candidate arsenic resistance variants in Drosophila melanogaster using NGS DNA sequencing (Illumina) - Conducted NGS sequencing analyses to identify significant alleles contributing to arsenic resistance (HPCC, Linux, Cytoscape)• Automated and optimized and pipeline of preprocessing large-scale raw data from Drosophila Activity Monitor assay (Python, Git/GitHub)• Led and collaborated with a team in conducting acute chemical exposure pilot screens using the Drosophila Genetic Reference Panel (DGRP); Statistically analyzed (SAS, R) and visualized the results (R)• Mentored undergraduate interns for Undergraduate Research Symposium

• Performed lifespan development experiment to identify novel interventions that extend longevity in ND2 Drosophila melanogaster Leigh syndrome fruit fly• Assisted screening of ~200 DGRP lines to investigate genetic variation in the development times in response to rapamycin

• Led a project which examined mitophagy of NDUFS mice under rapamycin treatments • Worked with the mouse team to collect mice tissues and extract brain proteins and DNA • Western blotted proteins from CST Mitochondrial Dynamics Antibody Sampler Kit, analyzed concentration through imageJ, interpreted the data and the results showed rapamycin reduces mitochondria fission

Master'S Degree, Genetics

Bachelor Of Arts - Ba, Biochemistry

Bachelor Of Science - Bs, Microbiology, General, 3.99