Subgroup Identification in targeted therapy development with time-to-event outcomes using a simultaneous inference procedure.Gene-based Association Analysis for Bivariate Time-to-event Data through Functional Regression with Copula Models.Experience on bulk RNA-seq, DNA methylation and metabolomics data analyses.Characterization the platelet trajectory of ICU patients using High Density Intensive Care (HIDENIC) database. Latent Class Mixed Model (LCMM) and hierarchical clustering methods were used.

Simulation studies on evaluating the disease-modifying effect in the delay-start design when intercurrent events exist

• Performed comprehensive data analysis to evaluate the Ligas consent decree

• Designed peptide models for beta hairpin structure, collected and analyzed experimental data using logistic regression model and linear regression model.• Investigated the function of Glutamate residue in a stack of β sheets in protein folding and unfolding using QM calculation and MD simulation.