Zack Sanborn

Zack Sanborn Email and Phone Number

Director, Computational Biology and Bioinformatics @ Cantata Bio
Zack Sanborn's Location
Santa Cruz, California, United States, United States
Zack Sanborn's Contact Details

Zack Sanborn work email

Zack Sanborn personal email

n/a
About Zack Sanborn

I truly love making data useful. My background in data science is both broad & deep, the result of working on numerous computationally-intensive projects in both academic and commercial settings. I have years of experience leading teams and developing tools that utilize a wide variety of data-driven analytical techniques to extract and present meaningful insights from complex datasets.Among my proudest accomplishments, I invented a highly accurate & efficient method to analyze terabytes of whole genome sequencing data from cancerous and normal biopsies to discover a wide range of somatic alterations. This technology was the foundation of a startup I co-founded (Five3 Genomics) that grew to employ over a hundred software engineers, scientists, and lab personnel and featured an in-house CLIA-validated high-throughput sequencing lab. My team and I developed a clinically-focused commercial product (GPS Cancer) that reported therapeutically-actionable alterations & findings from tumor DNA & RNA, helping guide treatments for thousands of patients from all over the country after just a few years on the market. We later refined GPS Cancer into a test called Omics Core, one of the first Tumor-Normal mutation profiling tests to be approved by FDA.

Zack Sanborn's Current Company Details
Cantata Bio

Cantata Bio

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Director, Computational Biology and Bioinformatics
Zack Sanborn Work Experience Details
  • Cantata Bio
    Director, Computational Biology And Bioinformatics
    Cantata Bio Jan 2024 - Present
    Scotts Valley, California, Us
  • Nanthealth
    Vice President, Research And Data Science
    Nanthealth May 2020 - Aug 2023
    Winterville, Nc, Us
    Conceived and guided the development of multiple company products using natural language processing (NLP) and machine learning techniques to improve how unstructured documents are utilized within both payer and provider workflows. Designed and implemented an image-based document similarity search of a large EMR document database using deep learning-based computer vision techniques. Led a team of data scientists to develop numerous novel data science methods & visualizations, including implementation of a medical document augmentation and summarization pipeline. Presented to multiple potential clients and internal/external stakeholders, including health insurance payers, providers, and healthcare data companies, helping spur the development of a data architecture plan capable of serving such analyses in a more robust and dynamic environment. Guided the development of company-wide data acquisition and enrichment strategies. Provided ongoing sequencing analysis and subject matter expertise to sister company ImmunityBio to support their drug pipelines and related FDA submissions, including the development of a first-of-its-kind NGS-based method to determine clonality of drug candidate cell lines that I invented. Designed a more robust & scalable computing infrastructure for sequencing data analysis onto which I rebuilt and tested Omics Core sequencing analysis pipelines.
  • Immunitybio
    Vice President, Applied Genomics
    Immunitybio Apr 2019 - May 2020
    San Diego, Ca, Us
    Developed Omics Core, a FDA-approved Tumor-Normal mutation profile test with a "true" estimate of tumor mutation burden based on whole exome sequencing data. Helping to build an immunotherapy-specific platform that integrates specialized technologies developed by the company with known biomarkers (DNA- or RNA-based) associated with immunotherapy efficacy.
  • Nantomics, Llc
    Vice President, Applied Genomics
    Nantomics, Llc Aug 2014 - Apr 2019
    Developed numerous tools used to analyze raw and processed sequencing data from tumor and normal tissue samples (DNA or RNA). Designed and developed a flexible, app-based platform for generating clinical and research-use-only reports from results of processed patient sequencing data, viewable on the web or PDF formats. These clinical reports were the basis of the GPS Cancer product, providing doctors with genomically-informed therapeutic recommendations to help treat thousands of cancer patients.
  • Five3 Genomics, Llc
    Chief Technology Officer
    Five3 Genomics, Llc Feb 2011 - Aug 2014
    Developed patented technology (BamBam) I spun out of the University of California, Santa Cruz into a commercial product, offering rapid sequencing alignment and analysis via a web-based platform.
  • Ucsc
    Graduate Student Researcher
    Ucsc Sep 2005 - Aug 2014
    Santa Cruz, Ca, Us
  • Ucsc
    Ph.D Candidate
    Ucsc Sep 2005 - Dec 2012
    Santa Cruz, Ca, Us
  • Naval Undersea Warfare Center
    Scientist
    Naval Undersea Warfare Center Jun 2001 - Sep 2005
    Newport, R.I., Us
    Designed & tested submarine sonar arrays. Developed algorithms for processing sonar data for signal localization & calibration.

Zack Sanborn Skills

Python Algorithms Genomics Bioinformatics R Computational Biology Genetics Sequencing Dna Sequencing Cancer Cancer Genomics Bam Dna C++ Sequencing Data Analysis

Zack Sanborn Education Details

  • University Of California, Santa Cruz
    University Of California, Santa Cruz
    Biomolecular Engineering And Bioinformatics
  • University Of California, Santa Cruz
    University Of California, Santa Cruz
    Bioinformatics
  • Harvey Mudd College
    Harvey Mudd College
    Applied Physics

Frequently Asked Questions about Zack Sanborn

What company does Zack Sanborn work for?

Zack Sanborn works for Cantata Bio

What is Zack Sanborn's role at the current company?

Zack Sanborn's current role is Director, Computational Biology and Bioinformatics.

What is Zack Sanborn's email address?

Zack Sanborn's email address is js****@****csc.edu

What schools did Zack Sanborn attend?

Zack Sanborn attended University Of California, Santa Cruz, University Of California, Santa Cruz, Harvey Mudd College.

What skills is Zack Sanborn known for?

Zack Sanborn has skills like Python, Algorithms, Genomics, Bioinformatics, R, Computational Biology, Genetics, Sequencing, Dna Sequencing, Cancer, Cancer Genomics, Bam.

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