Zachary Knotts Email and Phone Number
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I am a doctoral candidate at Brandeis University, specializing in cell and molecular biology with a focus on translational regulation during cellular stress. My research delves into the mechanisms transcripts use to bypass translational control, uncovering novel modes of initiation and their potential roles in aberrant translation, particularly in cancer biology.Previously, at the National Cancer Institute, I contributed to groundbreaking work on RP-182, a promising therapeutic that targets the tumor microenvironment. Our findings shed light on its potential to enhance anti-tumor immunity, paving the way for innovative cancer treatments.Throughout my academic and professional journey, I have been driven by a commitment to impactful scientific discovery. I thrive at the intersection of research and application, aiming to bridge fundamental biology with translational advancements that address critical challenges in human health.
Brandeis Graduate School Of Arts And Sciences
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Researcher Phd CandidateBrandeis Graduate School Of Arts And Sciences Aug 2019 - PresentMy dissertation research in the Marr lab has focused on uncovering the mechanisms that enable cellular transcripts to evade translational regulation during stress conditions.
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Cancer Research Training Award (Crta) FellowshipNational Cancer Institute (Nci) Oct 2017 - Jul 2019Bethesda, Md, UsUnder the guidance of Dr. Udo Rudloff, our lab discovered that RP-182 acts as a specific ligand for the CD206 receptor on pro-tumor M2 macrophages. This interaction induces autophagy and programmed cell death, transforming the tumor microenvironment into an anti-tumor state. -
Laboratory Assistant IiNational Cancer Institute (Nci) Aug 2016 - Oct 2017Bethesda, Md, UsInvestigating a mutant KRAS oncogene, G12D and G12R, and their profound role in the formation of pancreatic, lung, and colon cancer.
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Research AssistantUniversity Of Maryland Jan 2016 - Nov 2016College Park, Md, UsConducted research under Dr. Dwyer on microbial responses to cellular stress caused by beta-lactams, quinolones, and other antibiotics. Focused on understanding antibiotic resistance mechanisms and exploring novel strategies to disrupt bacterial resistance pathways. -
Laboratory Manager/Technician (Undergrad)University Of Maryland Sep 2015 - Dec 2015College Park, Md, UsThis lab works on the Host-Pathogen interactions, specifically with macrophages and the inflammatory response under the guidance of Dr. Mosser in the Cell Biology and Molecular Genetics program.
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Surgical Research Laboratory Intern (Undergrad)Tufts Medical Center Jun 2015 - Aug 2015Boston, Ma, UsWorked in the Surgical Research Laboratory at Tufts Medical Center under Dr. Perides, focusing on the pathogenesis of acute and chronic pancreatitis in mice. Gained hands-on experience with experimental research techniques and developed a deeper understanding of pancreatic disease mechanisms.
Zachary Knotts Skills
Zachary Knotts Education Details
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Brandeis UniversityCell/Cellular And Molecular Biology -
University Of MarylandCell Biology And Molecular Genetics
Frequently Asked Questions about Zachary Knotts
What company does Zachary Knotts work for?
Zachary Knotts works for Brandeis Graduate School Of Arts And Sciences
What is Zachary Knotts's role at the current company?
Zachary Knotts's current role is Researcher PhD Candidate | Molecular & Cellular Biology.
What is Zachary Knotts's email address?
Zachary Knotts's email address is zk****@****umd.edu
What schools did Zachary Knotts attend?
Zachary Knotts attended Brandeis University, University Of Maryland.
What are some of Zachary Knotts's interests?
Zachary Knotts has interest in Science And Technology, Education, Children.
What skills is Zachary Knotts known for?
Zachary Knotts has skills like Management, Microsoft Word, Microsoft Excel, Microsoft Office, Research, Public Speaking, Cell Culture, Molecular Biology, Laboratory, Powerpoint, Pcr, Gel Electrophoresis.
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