Researcher Phd Candidate
CurrentMy dissertation research in the Marr lab has focused on uncovering the mechanisms that enable cellular transcripts to evade translational regulation during stress conditions.
Aug 2019 - Present
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Zachary Knotts Email & Phone Number
Researcher Phd Candidate
at
Brandeis Graduate School of Arts and Sciences
1 work email found
@brandeis.edu
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Current company
Role
Researcher Phd Candidate
Location
Waltham, Massachusetts, United States
Who is Zachary Knotts? Overview
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Zachary Knotts is listed as Researcher Phd Candidate at Brandeis Graduate School of Arts and Sciences, based in Waltham, Massachusetts, United States. AeroLeads shows a work email signal at brandeis.edu and a matched LinkedIn profile for Zachary Knotts.
Zachary Knotts previously worked as Cancer Research Training Award (CRTA) Fellowship at National Cancer Institute (Nci) and Laboratory Assistant II at National Cancer Institute (Nci). Zachary Knotts holds Doctor Of Philosophy - Phd, Cell/Cellular And Molecular Biology from Brandeis University.
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Profile bio
About Zachary Knotts
I am a doctoral candidate at Brandeis University, specializing in cell and molecular biology with a focus on translational regulation during cellular stress. My research delves into the mechanisms transcripts use to bypass translational control, uncovering novel modes of initiation and their potential roles in aberrant translation, particularly in cancer biology.Previously, at the National Cancer Institute, I contributed to groundbreaking work on RP-182, a promising therapeutic that targets the tumor microenvironment. Our findings shed light on its potential to enhance anti-tumor immunity, paving the way for innovative cancer treatments.Throughout my academic and professional journey, I have been driven by a commitment to impactful scientific discovery. I thrive at the intersection of research and application, aiming to bridge fundamental biology with translational advancements that address critical challenges in human health.
Listed skills include Management, Microsoft Word, Microsoft Excel, Microsoft Office, and 12 others.
Current workplace
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Brandeis Graduate School Of Arts And Sciences
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6 roles
Zachary Knotts work experience
A career timeline built from the work history available for this profile.
Cancer Research Training Award (Crta) Fellowship
Under the guidance of Dr. Udo Rudloff, our lab discovered that RP-182 acts as a specific ligand for the CD206 receptor on pro-tumor M2 macrophages. This interaction induces autophagy and programmed cell death, transforming the tumor microenvironment into an anti-tumor state.
Oct 2017 - Jul 2019
Laboratory Assistant Ii
Investigating a mutant KRAS oncogene, G12D and G12R, and their profound role in the formation of pancreatic, lung, and colon cancer.
Aug 2016 - Oct 2017
Research Assistant
Conducted research under Dr. Dwyer on microbial responses to cellular stress caused by beta-lactams, quinolones, and other antibiotics. Focused on understanding antibiotic resistance mechanisms and exploring novel strategies to disrupt bacterial resistance pathways.
Jan 2016 - Nov 2016
Laboratory Manager/Technician (Undergrad)
This lab works on the Host-Pathogen interactions, specifically with macrophages and the inflammatory response under the guidance of Dr. Mosser in the Cell Biology and Molecular Genetics program.
Sep 2015 - Dec 2015
Surgical Research Laboratory Intern (Undergrad)
Worked in the Surgical Research Laboratory at Tufts Medical Center under Dr. Perides, focusing on the pathogenesis of acute and chronic pancreatitis in mice. Gained hands-on experience with experimental research techniques and developed a deeper understanding of pancreatic disease mechanisms.
Jun 2015 - Aug 2015
2 education records
Zachary Knotts education
Doctor Of Philosophy - Phd, Cell/Cellular And Molecular Biology
Brandeis University
Bachelor Of Science (Bs), Cell Biology And Molecular Genetics
University Of Maryland
FAQ
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What company does Zachary Knotts work for?
Zachary Knotts works for Brandeis Graduate School of Arts and Sciences.
What is Zachary Knotts's role at Brandeis Graduate School of Arts and Sciences?
Zachary Knotts is listed as Researcher Phd Candidate at Brandeis Graduate School of Arts and Sciences.
What is Zachary Knotts's email address?
AeroLeads has found 1 work email signal at @brandeis.edu for Zachary Knotts at Brandeis Graduate School of Arts and Sciences.
Where is Zachary Knotts based?
Zachary Knotts is based in Waltham, Massachusetts, United States while working with Brandeis Graduate School of Arts and Sciences.
What companies has Zachary Knotts worked for?
Zachary Knotts has worked for Brandeis Graduate School Of Arts And Sciences, National Cancer Institute (Nci), University Of Maryland, and Tufts Medical Center.
How can I contact Zachary Knotts?
You can use AeroLeads to view verified contact signals for Zachary Knotts at Brandeis Graduate School of Arts and Sciences, including work email, phone, and LinkedIn data when available.
What schools did Zachary Knotts attend?
Zachary Knotts holds Doctor Of Philosophy - Phd, Cell/Cellular And Molecular Biology from Brandeis University.
What skills is Zachary Knotts known for?
Zachary Knotts is listed with skills including Management, Microsoft Word, Microsoft Excel, Microsoft Office, Research, Public Speaking, Cell Culture, and Molecular Biology.
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