刘丹丹 Email & Phone Number

Suzhou, Cn

中国 江苏省 苏州

苏州君盟生物医药科技有限公司

中国 江苏省 苏州

苏州

Suzhou Industrial Park

1. I was mainly engaged in new antibody drug research and discovery for tumor immunotherapy, for instance, immune checkpoints and agonist targets.2. I was in charge of the antibody drug development and discovery independently, I have the ability of developing and conducting in vitro potency assays and in vivo efficacy study to support oncology drug discovery.3. In the passed two years, I was responsible for many antibody drug discovery projects and delivered two mAb lead molecules and… Show more 1. I was mainly engaged in new antibody drug research and discovery for tumor immunotherapy, for instance, immune checkpoints and agonist targets.2. I was in charge of the antibody drug development and discovery independently, I have the ability of developing and conducting in vitro potency assays and in vivo efficacy study to support oncology drug discovery.3. In the passed two years, I was responsible for many antibody drug discovery projects and delivered two mAb lead molecules and one bispecific antibody lead molecule to cell line group as project leader, which were pushed into CMC stage. 4. In the meantime, I published 2 patents on new drugs and participated in the work of antibody in vitro potency and toxicology study in preclinical stage for IND declaration. Show less

Shanghai

1. I mainly worked on cell-based assays for small molecule compound drug discovery. I have the capability to develop and conduct cell or biochemical based assays to support drug discovery. 2. Meanwhile I mainly worked on cancer immunotherapy and antibody drug discovery. I was familiar with in vitro function assays for antibody screening, including inflammatory reaction model，mixed lymphocyte reaction，T cell activation assay, macrophage phagocytosis assay, proliferation assays, etc. And I… Show more 1. I mainly worked on cell-based assays for small molecule compound drug discovery. I have the capability to develop and conduct cell or biochemical based assays to support drug discovery. 2. Meanwhile I mainly worked on cancer immunotherapy and antibody drug discovery. I was familiar with in vitro function assays for antibody screening, including inflammatory reaction model，mixed lymphocyte reaction，T cell activation assay, macrophage phagocytosis assay, proliferation assays, etc. And I had the ability to develop and perform in vitro potency assays targeted to different immune checkpoints, such as PD-1，PD-L1, OX40，VISTA，LAG3，IDO and so on.3. I mastered lots of in vitro biology technologies , for example real-time PCR, gene cloning, immunohistochemistry, ELISA, Western blot, cell culture ,cell transfection and so on. Extensive experience in BD FACS Calibur, Envision，Multidrop Combi and be good at data analysis using GraphPad Prism, XLfit, FlowJo and IDBS. Show less

Shanghai

At first, I was assigned to a veterinary drug production workshop to accumulate practical experiences and entered every procedure of injection and powder of veterinary medicine production ,such as raw materials preparation, washing bottles, filling and sealing, sterilizing, light inspection, packaging and so on. In addition, I was engaged in the quality testing of raw materials, semi-finished products and finished products in the quality monitoring department. Then I entered the R & D… Show more At first, I was assigned to a veterinary drug production workshop to accumulate practical experiences and entered every procedure of injection and powder of veterinary medicine production ,such as raw materials preparation, washing bottles, filling and sealing, sterilizing, light inspection, packaging and so on. In addition, I was engaged in the quality testing of raw materials, semi-finished products and finished products in the quality monitoring department. Then I entered the R & D department and was involved in the reseach of animals' interferon, in which I was mainly engaged in the construction of gene engineering bacteria, fermentation, inclusion body protein purification, protein electrophoresis, cell culture , cell-based detection of protein activity and so on. Show less

农学硕士, 基础兽医学, 以第一作者身份发表了四篇文章，中期考核优秀，

获得了“大象励志奖学金”一等奖，中期考核优秀及优秀毕业生

理学学士, 生物科学（动物方向）, 连续三年获得一等奖学金，每年平均分都在85分以上

获得“国家奖学金”及学校最高荣誉奖“校长奖”