利用结构生物学和蛋白质结构模拟手段,对抗体进行人源化和亲和力成熟改造,同时兼顾early-stage developability。人源化后的抗体亲和力下降不超过5倍,人源化程度不低于85%;亲和力成熟后的亲和力提高至少10倍。
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高级项目主管正大天晴 Sep 2017 - Present南京抗体工程
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抗体工程研究员Innovent Biologics, Inc. 信达生物制药(苏州)有限公司 Jul 2016 - Present中国苏州antibody engineering;antibody humanization;antibody affinity maturation;antibody early-stage developability optimization;antibody structure modeling.
Frequently Asked Questions about 王亮亮
What company does 王亮亮 work for?
王亮亮 works for Innovent Biologics, Inc. 信达生物制药(苏州)有限公司
What is 王亮亮's role at the current company?
王亮亮's current role is 研究员.
What schools did 王亮亮 attend?
王亮亮 attended 南京林业大学.
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