I. Current Main Performance : Phase I/II IND Approval by the FDA/MFDS for Oncolytic AdenovirusII. Process Development1. Cell Line Development 1.1. Insulin Glargine ProjectBy optimizing the leader sequence, our team increased productivity of the E.coli culture to 20g/L. 2. Upstream Process Development2.1. Botulinum Toxin Project Our team have developed a upstream process for producing drug substance from vegetable media.Using this process, our team have completed the production of non-clinical sample materials.2.2. Insuline Glargine ProjectBy optimizing the feeding strategy and media content, our team increased the productivity of the E.coli culture to 20g/L. 3. Downstream Process Development: Adenovirus Type5, Botulinum Toxin Type A, Insulin Glargine, Infliximab, Etanercept, Aflibercept, Erythropoietin, Interferon beta, HP-HMG (Highly Purified Human Menopausal Gonadotrophin),