4D Medicine Ltd

Parent company of the 4D Group, 4D Medicine Ltd is dedicated to shaping the future of implantable medical devices made from proprietary resorbable biomaterials. The 4D Group’s technology platform is centred around 4Degra®, a patent protected resorbable photocurable resin based on unique polycarbonate urethane chemistry. A result of 15 years rigorous academic research in leading U.K. universities, 4Degra® promises to free resorbable medical device design from historic constraints and overcome the clinical performance issues of current material options. The first medical devices to be made from this novel material is a range of interference screws for soft tissue-bone fixation that we plan to launch in the US market in early 2026. Other medical device products are under development and will be announced soon. Resorbable polymeric biomaterials haven’t changed fundamentally for decades. Although widely used in implantable medical devices, materials such as Polylactic Acid (PLA), Polycaprolactone (PCL), Poly Lactic-co-Glycolic Acid (PLGA) and their derivatives have delivered sub-optimal clinical performance with several key issues having been identified. 4Degra® is a resorbable biomaterial suited to a wide range of implantable medical device applications. It is a photocurable resin that can be processed into the finished device form by 3D printing, casting or conversion into thin films or meshes. Softer grades of 4Degra® exhibit excellent shape memory response, making them ideally suited for the manufacture of minimally invasive surgical devices including meshes, stents, films, and soft tissue scaffolds. Harder formulations are suited to more mechanically demanding uses such as trauma fixation plates, pins, screws, and load-bearing bone regeneration scaffolds.