Acs Division Of Medicinal Chemistry

Acs Division Of Medicinal Chemistry company information, Employees & Contact Information

The Medicinal Chemistry Division of the American Chemical Society is a professional association focused on connecting those with interests in drug discovery and development. We use chemistry as a tool to study human biology in order to make an impact on human health.
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Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group - ACS Publications

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group ACS Publications

Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8 - ACS Publications

Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8 ACS Publications

Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19 - ACS Publications

Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19 ACS Publications

Relevance of the Trillion-Sized Chemical Space “eXplore” as a Source for Drug Discovery - ACS Publications

Relevance of the Trillion-Sized Chemical Space “eXplore” as a Source for Drug Discovery ACS Publications

Practical High-Throughput Experimentation for Chemists | ACS Medicinal Chemistry Letters - ACS Publications

Practical High-Throughput Experimentation for Chemists | ACS Medicinal Chemistry Letters ACS Publications

Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid - ACS Publications

Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid ACS Publications

Perceptual Modifying Compounds and Their Potential Therapeutic Applications in Neuropsychiatric Disorders - ACS Publications

Perceptual Modifying Compounds and Their Potential Therapeutic Applications in Neuropsychiatric Disorders ACS Publications

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors - ACS Publications

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors ACS Publications

The Critical Role of Organic Chemistry in Drug Discovery - ACS Publications

The Critical Role of Organic Chemistry in Drug Discovery ACS Publications

Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2 - ACS Publications

Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2 ACS Publications

Why Decreasing Lipophilicity Alone Is Often Not a Reliable Strategy for Extending IV Half-life - ACS Publications

Why Decreasing Lipophilicity Alone Is Often Not a Reliable Strategy for Extending IV Half-life ACS Publications

Deuterium-Enabled Chiral Switching (DECS) Yields Chirally Pure Drugs from Chemically Interconverting Racemates - ACS Publications

Deuterium-Enabled Chiral Switching (DECS) Yields Chirally Pure Drugs from Chemically Interconverting Racemates ACS Publications

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells - ACS Publications

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells ACS Publications

Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2 - ACS Publications

Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2 ACS Publications

Emerging Utility of Fluorosulfate Chemical Probes - ACS Publications

Emerging Utility of Fluorosulfate Chemical Probes ACS Publications

Understanding and Improving the Membrane Permeability of VH032-Based PROTACs - ACS Publications

Understanding and Improving the Membrane Permeability of VH032-Based PROTACs ACS Publications

SMARCA2/4 PROTAC for Targeted Protein Degradation and Cancer Therapy - ACS Publications

SMARCA2/4 PROTAC for Targeted Protein Degradation and Cancer Therapy ACS Publications

mRNA Display Reaches for the Clinic with New PCSK9 Inhibitor - ACS Publications

mRNA Display Reaches for the Clinic with New PCSK9 Inhibitor ACS Publications

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors - ACS Publications

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors ACS Publications

Novel and High Affinity Fluorescent Ligands for the Serotonin Transporter Based on (S)-Citalopram - ACS Publications

Novel and High Affinity Fluorescent Ligands for the Serotonin Transporter Based on (S)-Citalopram ACS Publications

Optimization of Tubulysin Antibody–Drug Conjugates: A Case Study in Addressing ADC Metabolism - ACS Publications

Optimization of Tubulysin Antibody–Drug Conjugates: A Case Study in Addressing ADC Metabolism ACS Publications

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers - ACS Publications

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers ACS Publications

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT) - ACS Publications

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT) ACS Publications

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group - ACS Publications

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group ACS Publications

Fragment Screening by Surface Plasmon Resonance - ACS Publications

Fragment Screening by Surface Plasmon Resonance ACS Publications

Nanomaterials for (Nano)medicine - ACS Publications

Nanomaterials for (Nano)medicine ACS Publications

Identification of a New Series of STAT3 Inhibitors by Virtual Screening - ACS Publications

Identification of a New Series of STAT3 Inhibitors by Virtual Screening ACS Publications

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