Active Motif

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What is exciting about the area we work in Epigenomics is the systematic analysis of the global state of gene expression not attributable to mutational changes across the entire genome. Epigenetic mechanisms are affected by external factors including development in utero and in childhood, environmental chemicals, drugs and pharmaceuticals, aging, and diet. Changes to the epigenetic landscape can have a profound impact on health and disease. Precise mapping and measurement of the epigenetic landscape offers the promise of predictive biomarkers of disease development, even before changes in gene expression have taken place. Epigenomics is the “OME” connecting Genomics to Transcriptomics and Proteomics allowing a Multiomics approach to disease research which will result in a higher yield of data that can be aggregated and analyzed to become actionable information. What does Active Motif offer Epigenetic methods and approaches require the use of high-quality antibodies and enzymes that have undergone strict validation criteria. This allows the development of robust assays for use in mechanistic studies, translational medicine, drug discovery and diagnostics. Active Motif’s Product Development Program takes emerging novel techniques, and develops them into innovative products that allow researchers to perform the assays in their own labs as well as feeding into their end to end services pipeline. Active Motif is building a platform based on their patented transposase based technologies to simplify the interrogation of chromatin, the dynamics of histone modifications, chromatin remodeling, DNA methylation, transcription factor binding, as well as short and long range gene regulation by non-coding regulatory regions. Our bioinformatics platform can take the data generated by these techniques and provide powerful insights into the epigenetic changes occurring in disease or in response to drugs.

Company Details

Employees
106
Founded
-
Address
1914 Palomar Oaks Way, Ste. 150,belgium
Phone
49094039544910
Email
ch****@****tif.com
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
Carlsbad, California
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TIP -ChIP: T agmented, Inde x ed, and P ooled ChIP -Seq to Generate High-Throughput, Multi-Sample - researchgate.net

TIP -ChIP: T agmented, Inde x ed, and P ooled ChIP -Seq to Generate High-Throughput, Multi-Sample researchgate.net

Transcriptional landscape of the interaction of human Mesenchymal Stem Cells with Glioblastoma in bioprinted co-cultures - Stem Cell Research & Therapy

Transcriptional landscape of the interaction of human Mesenchymal Stem Cells with Glioblastoma in bioprinted co-cultures Stem Cell Research & Therapy

Advertorial: Directed Conjugation of Recombinant Antibodies - Genetic Engineering and Biotechnology News

Advertorial: Directed Conjugation of Recombinant Antibodies Genetic Engineering and Biotechnology News

Roth Capital Partners to Host a Virtual Healthcare Private Company Forum on June 28, 2021 - GlobeNewswire

Roth Capital Partners to Host a Virtual Healthcare Private Company Forum on June 28, 2021 GlobeNewswire

Epigenomic profiling of neuroblastoma cell lines - Nature

Epigenomic profiling of neuroblastoma cell lines Nature

What is DNA Methylation? - News-Medical

What is DNA Methylation? News-Medical

DNA base modification detection using single-molecule, real-time sequencing - Lab + Life Scientist

DNA base modification detection using single-molecule, real-time sequencing Lab + Life Scientist

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