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GDF8 and activin A blockade protects against GLP-1–induced muscle loss while enhancing fat loss in obese male mice and non-human primates Nature

Activin R for weight loss News-Medical

Principles of the activin receptor signaling pathway and its inhibition ScienceDirect.com

Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension American Heart Association Journals

Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas BMC Cancer

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2 ACS Publications

activation by Activin A‐induced receptor clustering and autophosphorylation EMBO Press

ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension Science | AAAS

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy PNAS

Activin B improves glucose metabolism via induction of Fgf21 and hepatic glucagon resistance Nature

Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype Cell Communication and Signaling

An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension Nature

GDF8 and activin A are the key negative regulators of muscle mass in postmenopausal females: a randomized phase I trial Nature

Activin E is a new guardian protecting against hepatic steatosis via inhibiting lipolysis in white adipose tissue Nature

Skeletal muscle endothelial dysfunction through the activin A–PGC1α axis drives progression of cancer cachexia Nature

Stepwise release of Activin-A from its inhibitory prodomain is modulated by cysteines and requires furin coexpression to promote melanoma growth | Communications Biology Nature

Sox9 inhibits Activin A to promote biliary maturation and branching morphogenesis Nature

Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds Nature

Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction Nature

Activin A more prominently regulates muscle mass in primates than does GDF8 Nature

Role of stromal activin A in human pancreatic cancer and metastasis in mice Nature

In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma Nature

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity PNAS

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva Nature

Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis Nature

Structure and activation of pro-activin A Nature

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity Science | AAAS

Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair Nature

Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury | Scientific Reports Nature

Regulation of hepcidin expression by inflammation-induced activin B Nature

Regulation of Drosophila hematopoietic sites by Activin-β from active sensory neurons Nature

ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A Science | AAAS

Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors Nature