Anavex Life Sciences Corp. (Nasdaq: AVXL) is a publicly traded biopharmaceutical company dedicated to the development of novel therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders, including Alzheimer's disease, Parkinson's disease, Rett syndrome, schizophrenia and other central nervous system (CNS) diseases, pain, and various types of cancer. Anavex's lead drug candidate, ANAVEX®2-73 (blarcamesine), has successfully completed a Phase 2a and a Phase 2b/3 clinical trial for Alzheimer's disease, a Phase 2 proof-of-concept study in Parkinson's disease dementia, and both a Phase 2 and a Phase 3 study in adult patients and one Phase 2/3 in pediatric patients with Rett syndrome. ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting SIGMAR1 and muscarinic receptors. Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer's disease. ANAVEX®2-73 also exhibited anticonvulsant, anti-amnesic, neuroprotective, and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy. The Michael J. Fox Foundation for Parkinson's Research previously awarded Anavex a research grant, which fully funded a preclinical study to develop ANAVEX®2-73 for the treatment of Parkinson's disease. We believe that ANAVEX®3-71, which targets SIGMAR1 and M1 muscarinic receptors, is a promising clinical stage drug candidate demonstrating disease-modifying activity against the major hallmarks of Alzheimer's disease in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid, and tau pathologies. In preclinical trials, ANAVEX®3-71 has shown beneficial effects on mitochondrial dysfunction and neuroinflammation. Further information is available at www.anavex.com.
Company Details
- Employees
- 45
- Address
- New York City, Ny 10019, Us
- Phone
- 14164890092
- in****@****vex.com
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- anavex.com
- Keywords
- jobs.
- HQ
- New York City, NY
Anavex Life Sciences Questions
Anavex Life Sciences's helpline number is 14164890092
Anavex Life Sciences's website is anavex.com
Anavex Life Sciences's LinkedIn profile is https://www.linkedin.com/company/anavex-life-sciences
Anavex Life Sciences has
45 employees.
View email and phone details for 45
employees at Anavex Life Sciences.
Anavex Life Sciences's industry is
Biotechnology Research
Anavex Life Sciences's top competitors are
Nuvation Bio,
Biospherix, Llc,
Royalty Pharma,
Tourmaline Bio,
Gilgamesh Pharmaceuticals,
Lexeo Therapeutics,
Dianthus Therapeutics, Inc.,
Immunic Therapeutics,
Envisagenics,
Protara Therapeutics.
Anavex Life Sciences's support email address is info@anavex.com
Anavex Life Sciences's categories are Biotechnology Research
