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Isosteric 3D Bicyclo[1.1.1]Pentane (BCP) Core-Based Lipids for mRNA Delivery and CRISPR/Cas Gene Editing ACS Publications

Discovery of Bi-magnolignan as a novel BRD4 inhibitor inducing apoptosis and DNA damage for cancer therapy ScienceDirect.com

Exploring the potential of TGFβ as a diagnostic marker and therapeutic target against cancer ScienceDirect.com

Interface Engineering of BCP Buffer Layers in Planar Heterojunction Perovskite Solar Cells With NiO Frontiers

BPS Publications British Pharmacological Society | Journals

BCP Buffer Layer Enables Efficient and Stable Dopant-Free P3HT Perovskite Solar Cells ACS Publications

Decarboxylative C–N Coupling of 2,2-Difluorobicyclo[1.1.1]pentane (BCP-F2) Building Blocks ACS Publications

Deregulation of lactate permeability using a small-molecule transporter (Lactrans-1) disturbs intracellular pH and triggers cancer cell death ScienceDirect.com

High Aspect Ratio Nanoscale Pores through BCP-Based Metal Oxide Masks and Advanced Dry Etching ACS Publications

Underappreciated roles for Rho GDP dissociation inhibitors (RhoGDIs) in cell function: Lessons learned from the pancreatic islet β-cell ScienceDirect.com

Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3/COX-2 crosstalk ScienceDirect.com

Multicomponent Synthesis of Alkyl BCP-Heteroaryls via Electron Donor–Acceptor Complex Photoactivation under Mild Conditions ACS Publications

KCNE4-dependent modulation of Kv1.3 pharmacology ScienceDirect.com

Metal-Free Photoredox Four-Component Strategy to 1,3-Functionalized BCP Derivatives ACS Publications

Targeted mutagenesis of negatively charged amino acids outlining the substrate translocation path within the human organic cation transporter 3 ScienceDirect.com

Proliferation and migration of PC-3 prostate cancer cells is counteracted by PPARγ-cladosporol binding-mediated apoptosis and a decreased lipid biosynthesis and accumulation ScienceDirect.com

Modulation of recognition memory performance by light and its relationship with cortical EEG theta and gamma activities ScienceDirect.com

Control of articular degeneration by extracellular vesicles from stem/stromal cells as a potential strategy for the treatment of osteoarthritis ScienceDirect.com

Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines ScienceDirect.com

Selected cannabis terpenes synergize with THC to produce increased CB1 receptor activation ScienceDirect.com

Light-enabled scalable synthesis of bicyclo[1.1.1]pentane halides and their functionalizations Nature

Vitamin D and the risk for cancer: A molecular analysis ScienceDirect.com

Exploring nanoarchitectonics and optical properties of PAA-ZnO@BCP wide-band-gap organic semiconductors Nature

Baby Connectome Project FNIH

Kinetic profiling and functional characterization of 8-phenylxanthine derivatives as A2B adenosine receptor antagonists ScienceDirect.com

BPS Publications British Pharmacological Society | Journals

Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma ScienceDirect.com

Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies ScienceDirect.com

Abscisic acid, an evolutionary conserved hormone: Biosynthesis, therapeutic and diagnostic applications in mammals ScienceDirect.com

Targeting nucleolin by RNA G-quadruplex-forming motif ScienceDirect.com

Malayoside, a cardenolide glycoside extracted from Antiaris toxicaria Lesch, induces apoptosis in human non-small lung cancer cells via MAPK-Nur77 signaling pathway ScienceDirect.com

The pharmacokinetics and the pharmacodynamics of cannabinoids British Pharmacological Society | Journals

Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases) ScienceDirect.com

Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors ScienceDirect.com

Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders British Pharmacological Society | Journals

BPS Publications British Pharmacological Society | Journals

Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer ScienceDirect.com

The druggability of bitter taste receptors for the treatment of neurodegenerative disorders ScienceDirect.com

BPS Publications British Pharmacological Society | Journals

The prospects for targeting FcR as a novel therapeutic strategy in rheumatoid arthritis ScienceDirect.com

Future prospects for mitosis-targeted antitumor therapies ScienceDirect.com

Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF-β induced epithelial to mesenchymal transition ScienceDirect.com

Uremic toxins activate CREB/ATF1 in endothelial cells related to chronic kidney disease ScienceDirect.com

Biological characterization of ligands targeting the human CC chemokine receptor 8 (CCR8) reveals the biased signaling properties of small molecule agonists ScienceDirect.com

BPS Publications British Pharmacological Society | Journals

Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology British Pharmacological Society | Journals

Wide awake at bedtime? Effects of caffeine on sleep and circadian timing in male adolescents – A randomized crossover trial ScienceDirect.com

Lomitapide - Goulooze - 2015 - British Journal of Clinical Pharmacology British Pharmacological Society | Journals

Evaluation of critical parameters in the hollow-fibre system for tuberculosis: A case study of moxifloxacin British Pharmacological Society | Journals

A General Route to Bicyclo[1.1.1]pentanes through Photoredox Catalysis ACS Publications

Characterisation of endogenous A2A and A2B receptor-mediated cyclic AMP responses in HEK 293 cells using the GloSensor™ biosensor: Evidence for an allosteric mechanism of action for the A2B-selective antagonist PSB 603 ScienceDirect.com

Bedaquiline - Goulooze - 2015 - British Journal of Clinical Pharmacology British Pharmacological Society | Journals

Osteoarthritis phenotypes and novel therapeutic targets ScienceDirect.com

Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide ScienceDirect.com

Fixed dosing of intravenous tocilizumab in rheumatoid arthritis. Results from a population pharmacokinetic analysis British Pharmacological Society | Journals

The pharmacodynamic and clinical trial evidence for statin dose British Pharmacological Society | Journals

Cerebral toxoplasmosis associated with treatment with rituximab, azathioprine and prednisone for dermatomyositis British Pharmacological Society | Journals

BPS Publications British Pharmacological Society | Journals

A review of the growing risk of vitamin D toxicity from inappropriate practice British Pharmacological Society | Journals

Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration ScienceDirect.com

Antimicrobial stewardship – can we afford to do without it? British Pharmacological Society | Journals

BPS Publications British Pharmacological Society | Journals

Potential therapeutic implications of cancer stem cells in glioblastoma ScienceDirect.com

Pathophysiology of proteinuria and its value as an outcome measure in chronic kidney disease British Pharmacological Society | Journals

Immediate-type hypersensitivity drug reactions British Pharmacological Society | Journals