Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company that is harnessing the power of bicyclic peptides and leveraging Nobel Prize-winning science to develop a new and differentiated class of medicines to treat cancer and other diseases. Bicycle® molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development.
The company is evaluating zelenectide pevedotin, previously BT8009, a Bicycle® Toxin Conjugate (BTC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radio Conjugates (BRC™) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.
Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA.
Company Details
- Employees
- 344
- Founded
- -
- Address
- Granta Park, Cambridge,england Cb21 6gp,united Kingdom
- Phone
- 44 1223 497 415
- in****@****ics.com
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- bicycletherapeutics.com
- HQ
- Cambridge, England
Bicycle Therapeutics Questions
Bicycle Therapeutics's helpline number is 44 1223 497 415
Bicycle Therapeutics's website is bicycletherapeutics.com
Bicycle Therapeutics's LinkedIn profile is https://www.linkedin.com/company/bicycle-therapeutics
Bicycle Therapeutics has
344 employees.
View email and phone details for 344
employees at Bicycle Therapeutics.
Bicycle Therapeutics's industry is
Biotechnology Research
Bicycle Therapeutics's top competitors are
Amphista Therapeutics Limited,
Alchemab Therapeutics Ltd,
Bit.bio,
Quell Therapeutics,
Astrazeneca,
Artios,
T-Therapeutics Ltd,
Vertex Pharmaceuticals,
Autolus Therapeutics,
Immunocore.
Bicycle Therapeutics's support email address is info@bicycletherapeutics.com
Bicycle Therapeutics's categories are Biotechnology Research
Bicycle Therapeutics's founding year is 2009
